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Sr. Research Scientist, Center for Alzheimer's

UT Southwestern Medical Center

Dallas, Texas, United StatesOn Site

Original Job Summary

About UT Southwestern

With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. Ranked as the number 1 hospital in Dallas-Fort Worth by U.S. News & World Report, it offers competitive benefits and abundant growth opportunities.

Position Overview

The Sr. Research Scientist, Center for Alzheimer's leads biomarker development for blood-based diagnostics in Alzheimer’s, Parkinson’s, and related neurodegenerative disorders.

Key Responsibilities

  • Lead assay optimization and validation for tau and alpha-synuclein biomarkers.
  • Coordinate with clinical investigators using patient and control samples.
  • Supervise and mentor laboratory personnel ensuring protocol adherence.
  • Collaborate with bioinformatics and biostatistics teams for data analysis.
  • Publish scientific findings and assist in grant writing.

Preferred Qualifications

Ph.D. in Neuroscience, Biochemistry, Molecular Biology or a related field with significant experience in biomarker assay development, immunoassays (SIMOA, ELISA), and neurodegenerative disease biology. Experience with Fc-VHH diagnostic tools and supervision of laboratory staff is valued.

Benefits

  • PPO medical plan available from day one
  • Preventive healthcare with 100% coverage
  • Paid Time Off and paid holidays
  • Retirement Programs through TRS
  • Tuition Reimbursement and Wellness Programs

Research Experience & Duties

Candidates must have significant research experience with roles involving development, analysis, and supervisory responsibilities in a scientific research project. The role includes drafting publications and contributing to grant proposals.

Security & EEO Statement

This position is security-sensitive and subject to criminal history record checks. UT Southwestern is an equal opportunity employer and is committed to diversity in its workforce.

Key skills/competency

Sr. Research Scientist, biomarker, assay, diagnostics, neurodegeneration, immunoassay, neuroscience, ELISA, SIMOA, mentorship

How to Get Hired at UT Southwestern Medical Center

🎯 Tips for Getting Hired

  • Customize Resume: Tailor your research experience for UT Southwestern.
  • Highlight Expertise: Focus on biomarker and assay development.
  • Showcase Publications: Include relevant high-impact journals.
  • Prepare for Interviews: Study technical and supervisory scenarios.

📝 Interview Preparation Advice

Technical Preparation

Review biomarker assay protocols.
Practice ELISA, SIMOA techniques.
Familiarize with protein purification methods.
Update on CSF and blood-based diagnostics.

Behavioral Questions

Describe past team leadership examples.
Explain conflict resolution in lab settings.
Discuss effective communication in collaborations.
Share experiences managing project deadlines.