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Regeneron

Associate Scientist - Protein Development

Regeneron · Tarrytown, NY

  • On site
  • Full-time
  • $110,000 / year
  • Tarrytown, NY

Job highlights

  • Purify and characterize protein reagents for therapeutic programs.
  • Utilize various chromatography and characterization techniques.
  • Analyze and document data in LIMS and presentations.
  • Collaborate with team members and communicate results.
  • Requires BS/MS and 0-2 years experience.

About the role

Associate Scientist - Protein Development

We are seeking an Associate Scientist to join the Protein Development group within our Therapeutic Proteins department. The candidate will join our ongoing efforts towards purification and characterization of protein reagents.

A Typical Day Might Include:

  • Purifying therapeutic reagents and antibodies for ongoing therapeutic programs using standard purification systems and automated equipment.
  • Conducting protein purification and characterization by liquid chromatography such as affinity, IEX, HIC, and SEC.
  • Performing protein characterization of reagents by Western blotting, SDS-PAGE electrophoresis, CE-SDS, SEC chromatography, spectrophotometry, etc.
  • Entering, analyzing, and documenting data of purified characterized reagents in LIMS and presentations.
  • Communicating results clearly and concisely to manager and peers.

This Role Might Be For You If You:

  • Can work productively in a fast-paced collaborative team.
  • Have strong organizational skills and excellent verbal and written communication skills.
  • Enjoy working productively in a fast-paced collaborative environment.
  • Have an eye for detail and pride yourself on the quality of your work.
  • Work on current problems while thinking of future solutions.

Qualifications:

To be considered for this role, you must have at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 0-2 years of relevant experience in protein purification/characterization. We need someone with a strong background in protein chemistry. Must have experience with liquid chromatography and isolation techniques such as Affinity, IEX, HIC, and SEC. AKTA Avant experience preferred. Experience purifying bispecific antibodies is very advantageous. Characterization experience of reagents by Western blotting, SDS-PAGE electrophoresis, CE-SDS, and SEC chromatography is also required. Must have experience with data entry and notebook keeping using ELN.

About Regeneron:

Regeneron is a leading global biotechnology company that invents, develops, and commercializes life-transforming medicines for people with serious diseases. Our success is driven by our unwavering commitment to scientific excellence, innovation, and a passion for making a difference in patients' lives. We offer an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels!

Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

Key skills/competency

  • Associate Scientist
  • Protein Development
  • Protein Purification
  • Protein Characterization
  • Liquid Chromatography
  • Western Blotting
  • SDS-PAGE
  • AKTA Avant
  • Bispecific Antibodies
  • Biochemistry

Skills & topics

  • Associate Scientist
  • Protein Development
  • Protein Purification
  • Protein Characterization
  • Biochemistry
  • Molecular Biology
  • Cellular Biology
  • Liquid Chromatography
  • AKTA Avant
  • Western Blotting
  • SDS-PAGE
  • Biotechnology
  • Pharma
  • Therapeutic Proteins
  • Antibody Purification

How to get hired

  • Tailor your resume: Highlight relevant protein purification and characterization experience, including specific techniques like affinity, IEX, HIC, SEC, Western blotting, and SDS-PAGE. Mention AKTA Avant if applicable.
  • Emphasize collaboration: Showcase your ability to work productively in fast-paced, collaborative teams and communicate results clearly.
  • Demonstrate attention to detail: Provide examples of your strong organizational skills and pride in the quality of your work.
  • Prepare for technical questions: Be ready to discuss your experience with protein chemistry, chromatography systems, and characterization methods.
  • Research Regeneron's culture: Understand their 'Regeneron Way,' commitment to scientific excellence, and inclusive culture.

Technical preparation

Master protein purification techniques (Affinity, IEX, HIC, SEC).,Practice various protein characterization methods.,Familiarize with AKTA Avant system operations.,Review ELN and LIMS data entry protocols.

Behavioral questions

Describe a complex purification challenge you solved.,How do you ensure data accuracy and quality?,Give an example of successful team collaboration.,How do you manage multiple projects effectively?

Frequently asked questions

What are the key protein purification techniques required for the Associate Scientist role at Regeneron?
For the Associate Scientist, Protein Development role at Regeneron, key protein purification techniques include affinity chromatography, ion-exchange (IEX), hydrophobic interaction (HIC), and size-exclusion chromatography (SEC). Experience with AKTA Avant is preferred.
What protein characterization methods should I highlight for this Associate Scientist position?
You should highlight experience with methods such as Western blotting, SDS-PAGE electrophoresis, CE-SDS, SEC chromatography, and spectrophotometry. Strong protein chemistry background is essential.
Is experience with bispecific antibodies important for the Associate Scientist role?
Yes, experience purifying bispecific antibodies is considered very advantageous for this Associate Scientist position at Regeneron, so be sure to mention it if you have it.
What educational background is preferred for the Associate Scientist, Protein Development job?
Regeneron prefers candidates with at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry, or a related field for this Associate Scientist position.
What is the expected level of experience for an Associate Scientist at Regeneron?
The Associate Scientist role at Regeneron typically requires 0-2 years of relevant experience in protein purification and characterization.
How does Regeneron approach teamwork and collaboration for their Associate Scientists?
Regeneron values a fast-paced, collaborative team environment. The Associate Scientist role requires the ability to work productively with peers and communicate results clearly to management and colleagues.
What data management and documentation skills are needed for this role?
The Associate Scientist role requires experience with data entry, analysis, and documentation using LIMS and ELN (electronic lab notebook) systems, as well as presenting findings.