NGS Data Scientist (Hybrid)
Quest Diagnostics · Lewisville, TX
- On site
- Full-time
- $120,000 / year
- Lewisville, TX
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Job highlights
- Analyze genomics data from NGS technologies.
- Develop bioinformatics pipelines for oncology products.
- Collaborate with cross-functional R&D teams.
- Interpret complex genomics data for insights.
- Work hybrid in Lewisville, TX facility.
About the role
NGS Data Scientist - Oncology Assay Development
We are seeking a highly motivated next generation sequencing (NGS) data analytic scientist to support Oncology Assay Development at Quest. As a member of the Oncology R&D team, this role will collaborate with other scientists and staff from cross-functional teams to develop, validate, and support cutting-edge genomic assays for oncology applications.
The ideal candidate will have a strong background in bioinformatics and/or genomic data analysis for somatic applications, translating complex data into actionable insights that drive product development, operational excellence and clinical impact.
This professional will work in a hybrid capacity requiring 3 days onsite at our Lewisville, TX facility.
Responsibilities
- Perform bioinformatic analysis of genomics data from next generation sequencing. Specific data types include whole exome sequencing (WES), whole exome sequencing (WGS), and targeted DNA and RNA panel datasets generated from Illumina, Ion Torrent and PacBio sequencing technologies.
- Curate, analyze, and interpret complex genomics datasets to support assay development, validation, and high throughput implementation
- Present findings to drive decision-making in R&D product development, troubleshooting, and pipeline improvement
- Design, develop, and deploy scalable and robust bioinformatics pipelines to support analytical validation data analysis for new oncology products
- Partner with R&D, automation, laboratory operations, and software teams to understand and address the technical challenges and implement efficient solutions
- Support production day-to-day operations, quickly pivoting focus to respond to incidents and requests
- Monitor, execute, and improve sequence analysis workflows and automation
- Produce charts and visualization for dashboards, reporting, and in support of data driven hypothesis testing
- Track, troubleshoot and mitigate issues encountered in processing production samples to meet strict Turnaround Times (TAT)
- Contribute to continuous improvement of analytical methods, workflows, and data quality standards
Qualifications
The ideal candidate will have a history of using bioinformatic technical skills to deliver accurate and timely results.
Required Work Experience
- Requires at least 4 (four) years of relevant industrial experience in data science and/or bioinformatics role
- Master's degree, or a Ph.D. in bioinformatics, computational biology, molecular biology, chemistry, physics, statistics, or a related field
- Experience with oncology genomics and somatic variant analysis
Preferred Work Experience
- Experience in NGS workflow development
- Strong analytical skills with the ability to interpret and communicate experimental results
- Ability to work collaboratively in a fast-paced, Cross-functional environment.
- Experience with Software Development Life Cycle documentation procedure
- Familiarity with assay validation, regulatory environment (CAP/CLIA), or clinical diagnostics
Skills
- Experience using scripting languages (Python, R, or similar) for scientific data analysis and visualization
- Strong proficiency in NGS data processing, QC, and interpretation
- Experience with analysis of next-generation sequencing data, preferably including Whole-Genome Sequencing, Variant calling, and Annotation
- Excellent communication skills and the desire to work in a dynamic and collaborative environment
About The Team
Quest Diagnostics honors our service members and encourages veterans to apply. While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.
Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.
Key skills/competency
- NGS Data Scientist
- Bioinformatics
- Genomic Data Analysis
- Oncology Genomics
- Somatic Variant Analysis
- Python
- R
- Illumina
- Ion Torrent
- PacBio
Skills & topics
- NGS Data Scientist
- Bioinformatics
- Genomics
- Oncology
- Data Analysis
- Python
- R
- Illumina
- Variant Calling
- Somatic Analysis
- Quest Diagnostics
- Lewisville
- TX
- Hybrid
- Master's Degree
- PhD
How to get hired
- Tailor your resume: Highlight relevant experience in bioinformatics, NGS data analysis, and oncology genomics, using keywords from the job description.
- Showcase your skills: Emphasize your proficiency in Python/R, NGS data processing, and variant calling to demonstrate technical readiness.
- Quantify achievements: Use numbers to illustrate your impact in previous roles, such as pipeline efficiency improvements or TAT reductions.
- Prepare for hybrid work: Be ready to discuss your ability to collaborate effectively in a hybrid environment and your commitment to onsite presence.
- Research Quest Diagnostics: Understand their mission in oncology and diagnostics to align your application with their goals.
Technical preparation
Master Python/R for bioinformatics analysis.,Practice NGS data QC and variant calling.,Familiarize with WES, WGS, and panel data.,Study Illumina, Ion Torrent, PacBio platforms.
Behavioral questions
Describe a complex data challenge solved.,How do you collaborate in cross-functional teams?,How do you handle tight deadlines (TAT)?,Share an example of pipeline improvement.
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Frequently asked questions
- What are the key responsibilities for an NGS Data Scientist at Quest Diagnostics?
- As an NGS Data Scientist at Quest Diagnostics, your key responsibilities will include performing bioinformatic analysis of genomics data, curating and interpreting complex datasets, designing and deploying bioinformatics pipelines, and collaborating with cross-functional teams to support oncology assay development and product launches. You will also be involved in supporting production operations and continuous improvement of analytical methods.
- What educational background is required for the NGS Data Scientist role?
- The role requires a Master's degree or a Ph.D. in a related field such as bioinformatics, computational biology, molecular biology, chemistry, physics, or statistics. This advanced academic background is crucial for the complex data analysis and interpretation involved in oncology genomics.
- How much experience is needed to be considered for the NGS Data Scientist position?
- Quest Diagnostics requires at least four years of relevant industrial experience in a data science and/or bioinformatics role. Additionally, experience with oncology genomics and somatic variant analysis is essential for this position.
- What specific NGS technologies and data types are relevant for this role?
- The NGS Data Scientist will work with data types such as whole exome sequencing (WES), whole genome sequencing (WGS), and targeted DNA and RNA panels. Experience with data generated from Illumina, Ion Torrent, and PacBio sequencing technologies is highly valued.
- What programming languages and tools are most important for this NGS Data Scientist job?
- Proficiency in scripting languages like Python and R for scientific data analysis and visualization is a must. Strong skills in NGS data processing, quality control, interpretation, variant calling, and annotation are also critical for success in this role.
- What is the work arrangement for the NGS Data Scientist at Quest Diagnostics?
- This is a hybrid position, requiring the employee to be onsite at the Lewisville, TX facility for 3 days per week, with the remaining days offering remote work flexibility.
- Does Quest Diagnostics encourage veterans to apply for the NGS Data Scientist role?
- Yes, Quest Diagnostics actively honors service members and encourages veterans to apply for positions like the NGS Data Scientist role. They value the skills and experience that veterans bring to the team.
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