Clinical Research Associate II
Piper Companies · United States
- Hybrid
- Full-time
- $110,000 / year
- United States
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Job highlights
- Remote CRA II role in life sciences industry.
- Support cardiovascular, CNS, and metabolic studies.
- Monitor sites, ensure GCP and regulatory compliance.
- Requires 1-4 years clinical monitoring experience.
- Bachelor's degree and specific therapeutic area knowledge.
About the role
About the Role
Piper Companies is seeking a Clinical Research Associate II to join a global organization within the clinical research and life sciences industry. This is a remote permanent role requiring 60-75% travel across the United States. The CRA II will support cardiovascular, CNS, and metabolic studies, partnering closely with investigative sites to ensure high-quality trial execution.
Responsibilities
- Perform routine and close-out monitoring visits to ensure studies align with GCP, ICH, and applicable regulations.
- Serve as the primary point of contact for assigned research sites, fostering strong relationships and ongoing communication.
- Review site data, source documentation, and regulatory files for accuracy, completeness, and protocol adherence.
- Provide guidance and training to site staff on protocol requirements, study procedures, and compliance expectations.
- Identify, document, and escalate quality or compliance concerns, supporting resolution efforts.
Qualifications
- 1–4 years of onsite clinical monitoring experience (CRA II or Senior CRA I level).
- Experience supporting clinical trials in cardiovascular, CNS, diabetes, or metabolic indications.
- Strong working knowledge of GCP, ICH guidelines, and FDA regulatory requirements.
- Proficiency with CTMS, EDC systems, and standard clinical trial documentation.
- Bachelor’s degree in life sciences, nursing, or a related discipline. Spanish fluency is highly preferred for candidates in Florida or Puerto Rico.
Compensation and Benefits
Salary Range: $100,000–$110,000/year (USD)
Comprehensive Benefits: Medical, Dental, Vision, sick leave (if required by law), and 401(k).
Key Skills/Competency
- Clinical Research
- Clinical Trials
- CRA
- GCP
- ICH
- Regulatory Compliance
- Site Monitoring
- Clinical Monitoring
- CTMS
- EDC
Skills & topics
- Clinical Research Associate
- Clinical Trials
- CRA
- GCP
- ICH
- Regulatory Compliance
- Site Monitoring
- Clinical Monitoring
- CTMS
- EDC
- Cardiovascular Studies
- CNS Trials
- Diabetes Research
- GLP-1
- Site Management
- FDA Regulations
- Clinical Operations
- Documentation
- Quality Assurance
- Protocol Compliance
- Investigator Sites
- Patient Safety
- Clinical Development
- Remote
- Life Sciences
How to get hired
- Tailor your resume: Highlight your 1-4 years of clinical monitoring experience, GCP/ICH knowledge, and specific therapeutic area expertise (cardiovascular, CNS, metabolic).
- Showcase technical skills: Emphasize your proficiency with CTMS, EDC systems, and clinical trial documentation.
- Demonstrate compliance knowledge: Clearly articulate your understanding of FDA regulations and your ability to ensure protocol adherence.
- Address location and language: If applying from Florida or Puerto Rico, highlight any Spanish fluency.
Technical preparation
Master GCP, ICH, and FDA regulations.,Practice CTMS and EDC system navigation.,Review clinical trial documentation examples.,Study cardiovascular, CNS, metabolic protocols.
Behavioral questions
Describe a time you ensured site compliance.,How do you manage site relationships remotely?,How do you handle escalating quality concerns?,Share an experience training site staff.
Frequently asked questions
- What is the salary range for a Clinical Research Associate II at Piper Companies?
- The Clinical Research Associate II position at Piper Companies offers a competitive salary range of $100,000 to $110,000 per year, along with a comprehensive benefits package.
- Is this a remote position, and what is the travel expectation for the CRA II role?
- Yes, this is a permanent remote position. However, it requires significant travel, estimated at 60-75% across the United States, to perform monitoring visits at investigative sites.
- What therapeutic areas does the Clinical Research Associate II focus on?
- The Clinical Research Associate II will primarily support clinical trials within the cardiovascular, CNS, and metabolic indications, including areas like diabetes research and GLP-1 studies.
- What are the essential qualifications for the Clinical Research Associate II role?
- Key qualifications include 1-4 years of onsite clinical monitoring experience, a strong understanding of GCP, ICH, and FDA regulations, proficiency with CTMS/EDC systems, and a Bachelor's degree in a relevant life science field.
- Does Piper Companies require specific software proficiency for the CRA II position?
- Yes, proficiency with Clinical Trial Management Systems (CTMS), Electronic Data Capture (EDC) systems, and standard clinical trial documentation is a required qualification for this role.
- Is Spanish fluency a requirement for the Clinical Research Associate II role?
- Spanish fluency is highly preferred, particularly for candidates based in Florida or Puerto Rico, though it is not a strict requirement for all applicants.
- What type of benefits does Piper Companies offer for this Clinical Research Associate II position?
- Piper Companies provides a comprehensive benefits package including Medical, Dental, Vision insurance, sick leave (as required by law), and a 401(k) plan.
- How long will applications be accepted for the Clinical Research Associate II position?
- Applications for this Clinical Research Associate II role will be accepted for at least 30 days from the posting date of May 29, 2026.