Scientist I – MSAT (Cell & Gene Therapy) @ Legend Biotech US
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About Legend Biotech
Legend Biotech is a global biotechnology company dedicated to treating and one day curing life-threatening diseases. Headquartered in Somerset, New Jersey, the company is at the forefront of developing advanced cell therapies, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. Their global operations support the discovery of safe and efficacious therapeutics for patients worldwide.
Collaboration & Strategic Partnership
Legend Biotech has entered into a global collaboration with Janssen, a pharmaceutical company under Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel), aimed at treating multiple myeloma.
Role Overview
The Scientist I – MSAT (Cell & Gene Therapy) plays a vital role within the Manufacturing Technology team in Somerset, NJ. The role involves supporting the development, troubleshooting, and optimization of automated manufacturing processes for CAR-T and other cell therapy products under the guidance of senior staff.
Key Responsibilities
- Execute bench-scale experiments for bio-pilot runs, technology evaluations, and process improvements.
- Operate and troubleshoot closed-system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G-Rex).
- Perform and interpret analytical assays, including flow cytometry, qPCR, ELISA, and cell-based methods.
- Collect, analyze, and summarize experimental data using statistical tools.
- Assist in the preparation of study protocols, technical reports, and SOPs in compliance with GMP standards.
- Support process troubleshooting and root-cause investigations for manufacturing systems.
- Maintain a safe, organized, and compliant laboratory workspace.
Requirements
- Bachelor’s degree in biotechnology, bioengineering, molecular biology, or related discipline.
- 2-4 years’ experience in cell culture in academic, process development, or GMP environments.
- Hands-on expertise with aseptic technique and biosafety cabinet work.
- Exposure to closed-system or automated manufacturing platforms and analytical assays.
- Proficiency with data analysis and technical documentation preparation.
- Familiarity with Microsoft Office and basic statistical tools.
Benefits & EEO Statement
Legend Biotech offers a comprehensive benefits package including medical, dental, vision, 401(k) with company match, parental leave, paid time off, and additional benefits. They are an equal opportunity employer committed to diversity and inclusion.
Key skills/competency
Scientist I – MSAT (Cell & Gene Therapy); cell culture; GMP; automated platforms; analytical assays; troubleshooting; process optimization; bio-pilot experimentation; technical documentation; data analysis
How to Get Hired at Legend Biotech US
🎯 Tips for Getting Hired
- Customize your resume: Tailor it to cell therapy and MSAT skills.
- Highlight GMP experience: Emphasize process improvements and troubleshooting competencies.
- Research Legend Biotech: Understand their collaboration and technologies.
- Prepare for technical interviews: Focus on assay and data analysis insights.