Senior Research Scientist @ ICON plc
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About the Role
ICON plc is a world-leading healthcare intelligence and clinical research organization. We are looking for a Senior Research Scientist to join our team in Cambridge, MA on site. In this role, you will design, conduct, and analyze complex clinical research studies and drive innovative research initiatives.
Responsibilities
- Design, develop, and validate multiplex immunofluorescence assays using platforms such as Akoya Biosciences, Leica Bond RX, or similar.
- Perform tissue staining, imaging, and quantitative analysis of FFPE and frozen tissue samples.
- Collaborate with pathologists, bioinformaticians, and project teams to interpret spatial biology data.
- Optimize antibody panels, fluorophore selection, and signal amplification strategies.
- Maintain detailed experimental records ensuring data integrity and reproducibility.
- Mentor junior scientists in mIF techniques and best practices.
- Contribute to scientific publications, regulatory submissions, and presentations.
- Manage assay validations, experiments, and data analysis independently.
- Educate colleagues on new testing methods and technologies.
- Assist in developing proposals, pricing, and transferring assays to other ICON labs.
Preferred Experience
Experience in a GLP/GCLP or CLIA-regulated environment. Familiarity with digital pathology and integration of mIF data with other omics platforms. Prior involvement in clinical trial biomarker development or companion diagnostics is desirable.
Qualifications
Ph.D. in Immunology, Pathology, Molecular Biology, or a related field with 5+ years of relevant experience. Alternatively, MS or BS with appropriate experience may be considered. Must have proven expertise in multiplex immunofluorescence including panel design, antibody validation, and image analysis. Hands-on experience with automated staining platforms and imaging systems, as well as proficiency in image analysis software, is required.
What ICON Offers
Along with a competitive salary, ICON offers comprehensive benefits including various annual leave entitlements, health insurance options, and retirement planning. Additional perks include global employee assistance programs, flexible benefits like childcare vouchers, fitness subsidies, and more.
Key Skills/Competency
Senior Research Scientist, multiplex immunofluorescence, clinical trials, assay validation, tissue staining, image analysis, digital pathology, spatial biology, regulatory submissions, mentoring.
How to Get Hired at ICON plc
🎯 Tips for Getting Hired
- Research ICON's culture: Understand their mission and inclusive work environment.
- Customize your resume: Highlight clinical research and mIF expertise.
- Prepare for technical interviews: Review multiplex assay techniques.
- Showcase teamwork: Emphasize collaboration with cross-functional teams.