Staff Bioinformatics Scientist @ Guardant Health
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Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights through advanced blood and tissue tests, real-world data and AI analytics. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Job Description
The Staff Bioinformatics Scientist will work within the bioinformatics group to develop computational models for screening (Shield™) and oncology products (e.g., Guardant360®). The role involves developing, prototyping, and analyzing novel statistical/machine learning models to improve early cancer detection, minimal residual disease detection, longitudinal monitoring of treatment response, and cancer-signal-origin prediction.
- Develop and analyze statistical/machine learning models.
- Collaborate cross-functionally with various teams.
- Integrate external genomic, epigenomic and proteomic data.
- Create interactive tools and dashboards.
- Document code and produce reproducible analyses.
Qualifications
A Ph.D. in computational biology, bioinformatics, genomics, machine learning or a related field and a minimum of 8 years related experience. Proficiency in Python, R, data visualization, and handling large data lakes is required.
Preferred skills include a background in cancer biology/epigenetics, experience with public datasets (TCGA, ENCODE), Linux command-line and version control (git), and high-performance computing infrastructures.
Additional Information
This full-time role is based in either Palo Alto or San Diego. It follows a hybrid work model, requiring on-site work on specific days for employees within 50 miles of a facility. Salary ranges between $174,700 and $240,250, excluding benefits, bonus, commission, or equity.
Guardant Health is committed to equal opportunity employment and provides reasonable accommodations for candidates with disabilities.
Key skills/competency
- Bioinformatics
- Machine Learning
- Statistical Modeling
- Data Integration
- Python
- R
- Data Visualization
- Genomics
- Epigenomics
- High-performance Computing
How to Get Hired at Guardant Health
🎯 Tips for Getting Hired
- Customize your resume: Highlight relevant bioinformatics and ML skills.
- Tailor your cover letter: Detail your genomic data experience.
- Research Guardant Health: Study their precision oncology approach and products.
- Prepare for technical interviews: Practice coding and model design questions.