Senior Scientist, Pharmacology CVRM

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech!

The Opportunity

In this position, you will be leading the pharmacology efforts to drive discovery to identify new lead molecules, and design and execute mechanistic studies to characterize these compounds and their impact on physiology and pathophysiology. In addition, you will help evaluate literature information and novel assay formats to ensure rapid progress and overall project success. This position requires working closely with scientists in a multidisciplinary team. Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. At Genentech we value diverse perspectives and encourage our scientists to contribute at multiple levels within the company, including strategic development.

Primary Responsibilities

• Provide scientific and technical hands-on support for research involving but not limited to in vivo and ex vivo studies in animal models of cardiovascular diseases, diabetes, obesity, and metabolic related diseases with the goal of progressing novel drug candidates into clinical development and beyond.
• Plan and execute experiments, develop and follow protocols, document data, troubleshoot problems, interpret data and communicate results, and maintain up-to-date knowledge in the fields.
• Mentor and train junior members to be scientifically and technically proficient.
• Manage studies performed at CROs, evaluate the resulting data, develop technical documents and assist with the preparation and/or review of information supporting regulatory submissions.
• Work collaboratively within multidisciplinary project teams.
• Effectively communicate results to team members and collaborators.

Who You Are

• PhD in Pharmacology, Biology or other related field with relevant post-graduate experience. Knowledge in the cardio-metabolic disease field with a strong in vivo background is essential.
• A scientist with passion for hands-on research and desire to lead from the bench.
• Ability to multitask and contribute to several projects while remaining well organized.
• Good interpersonal skills and ability to work well with a multidisciplinary team.
• Ability to take unique and creative approaches to solve challenging problems.

Preferred Qualifications

• Experience in rodent surgeries, ex vivo experiments, and isolation of primary cells is a plus.
• Prior experience working in a biotech or pharmaceutical industry setting, understanding the demands and timelines of a drug discovery and development environment.

Key skills/competency

• Pharmacology
• In Vivo Studies
• Cardiovascular Diseases
• Metabolic Diseases
• Drug Discovery
• Preclinical Development
• Mechanistic Studies
• Data Interpretation
• Scientific Leadership
• CRO Management