Senior Research Investigator, Clinical Pharmacology & Pharmacometrics

Working with Us at Bristol Myers Squibb

Working at Bristol Myers Squibb offers a challenging, meaningful, and life-changing experience. Here, uniquely interesting work happens every day, from optimizing production lines to breakthroughs in cell therapy, transforming patients' lives and the careers of those involved. You'll grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams, taking your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility, offering a wide variety of competitive benefits, services, and programs to support employees' goals, both at work and in their personal lives. More details can be found at careers.bms.com/working-with-us.

Position Summary for Senior Research Investigator, Clinical Pharmacology & Pharmacometrics

Clinical Pharmacology & Pharmacometrics plays a key role in the drug development process. This involves planning, designing, and executing clinical pharmacology studies while maximizing model-informed drug development (MIDD) to drive decisions throughout the clinical program. Senior Research Investigators in this group function in a blended role, combining classical clinical pharmacology with quantitative analysis skills. Given the breadth of the portfolio, Senior Research Investigators will lead clinical pharmacology and pharmacometrics efforts on compounds in both early and late stages of development, including small and large molecules.

The CP&P team at BMS is responsible for providing pharmacology and pharmacometric support for all pipeline assets across the entire clinical development lifecycle. This team interacts with discovery and translational scientists, project leadership, early development, late development, and commercial colleagues to optimize dosing, formulation, delivery, and combination strategies. This enables faster and more effective drug development, informed by core scientific principles and data.

Key Responsibilities

• Contributes to compound development across various therapeutic areas and the design of clinical studies, with some supervision.
• Leads the design of clinical pharmacology studies and manages data analysis, interpretation, and reporting.
• Proficient in PK, PK/PD, and model-informed drug development (MIDD) principles and analyses.
• Collaborates on cross-functional drug development teams, regulatory submissions, and departmental initiatives.
• Participates in interactions with health authorities.
• Contributes to and owns modeling and simulation plans.
• With some supervision, contributes to clinical development strategies of pipeline products.

Qualifications & Experience

• Advanced Degree in a related field (MS, Ph.D. or PharmD).
• Approximately 2+ years experience with demonstrated progression in clinical pharmacology and pharmacometrics knowledge.
• General knowledge of the general drug development process.
• Quantitative data analysis, POP PK/PD, and data visualization skills.
• Programming familiarity experience (e.g., NONMEN, R, WinNonlin, SAS, Splus, etc.).

If a role intrigues you but doesn't perfectly line up with your resume, Bristol Myers Squibb encourages you to apply. You could be one step away from work that will transform your life and career.

Compensation Overview

The starting compensation range for this full-time employee (FTE) role is listed above. Additional incentive cash and stock opportunities (based on eligibility) may be available. Final individual compensation is decided based on demonstrated experience, taking into account job characteristics like required skills, location, work schedule, knowledge, and experience.

Benefits are subject to the terms and conditions of applicable plans and may require enrollment. Offerings include Health Coverage (Medical, pharmacy, dental, vision), Wellbeing Support (BMS Well-Being Account, BMS Living Life Better, EAP), and Financial Well-being and Protection (401(k), disability, life insurance, etc.). Work-life benefits include Paid Time Off, with flexible time off for US Exempt Employees (unlimited, with manager approval) and 11 paid national holidays. Additional time off may include unlimited paid sick time, volunteer days, summer hours flexibility, and various leaves of absence, plus an annual Global Shutdown between Christmas and New Years Day.

On-site Protocol

BMS operates with an occupancy structure including site-essential, site-by-design, field-based, and remote-by-design jobs. Site-by-design roles, which this position may fall under, are eligible for a hybrid work model with at least 50% onsite presence, considered essential for collaboration, innovation, productivity, and Company culture.

Key skills/competency

• Clinical Pharmacology
• Pharmacometrics
• Drug Development
• Quantitative Analysis
• PK/PD Modeling
• NONMEN
• R Programming
• SAS
• WinNonlin
• Regulatory Submissions