Principal Scientist Molecular Design

@ BioSpace

Company Overview

Terray Therapeutics is a venture-backed biotechnology company led by pioneers in artificial intelligence, synthetic chemistry, automation, and nanotechnology. They generate chemical data at an unprecedented scale to propel drug discovery into the information age.

Position Summary

As a Principal Scientist Molecular Design, you will join the Computational and Data Sciences (CDS) team to guide design efforts on advancing programs from hit exploration to lead optimization. You will leverage vast chemical datasets and proprietary platforms, working closely with chemistry, biology, and machine learning teams.

Core Responsibilities

• Lead multiple pipeline programs through hit exploration and hit-to-lead stages.
• Manage direct reports across pipeline projects.
• Design small molecules using in-house high-throughput computational tools.
• Collaborate with Molecular Design, Machine Learning, and Medicinal Chemistry teams.
• Communicate design strategies and outcomes internally and externally.

Experience and Qualifications

The candidate should have a BS/MS/PhD in computational, organic, or medicinal chemistry or related field with 7+ years in the industry. Publications, patents, and experience with ligand-based and structure-based methods, large chemical datasets, and familiarity with Python and RDKit are required.

Compensation and Benefits

Compensation ranges from $195,000 to $294,000 annually, including participation in the company's option plan, a 3% retirement safe harbor contribution, and fully-paid medical, dental, vision, life, and disability benefits.

Key skills/competency

• Molecular Design
• Computational Chemistry
• Medicinal Chemistry
• Drug Discovery
• Data Analysis
• Team Leadership
• Python
• RDKit
• High-throughput Screening
• Interdisciplinary Collaboration