Molecular Genetics Analysis Assistant QC

Molecular Genetics Analysis Assistant QC

Baylor Genetics, a global leader in clinical molecular genetics, is seeking a Sr. Molecular Genetics Analysis Assistant for its Clinical Genomics Interpretation (CGI) division. This role is crucial for ensuring the quality and accuracy of genetic sequencing data.

Duties And Responsibilities

• 25%: Perform quality control review of clinical samples and Next-Generation Sequencing (NGS) data.
• 50%: Analyze clinical genomics data, including variant identity using HGVS standards, variant checking in IGV, trinucleotide repeat analysis, and ordering confirmation testing.
• 25%: Monitor case tracking and turnaround times.

Qualifications/Experience

• Bachelor of Science (BS) in Genetics or a related field required. Master’s, PhD, MD, and/or MB(ASCP) desired.
• Minimum of 7+ years of relevant experience.
• Strongly preferred experience in pharmacogenomics (PGx) variant calling, especially with complex loci like CYP2D6.
• Proven track record in high-quality work, leading projects to completion, deep understanding of complex variant analysis, broad expertise, training coworkers, and workflow process improvement.
• Required: Familiarity with HGVS variant nomenclature standards.
• Expertise in clinical medicine, genetics, genomics, or molecular biology concepts.
• Experience in data quality assessment and effective communication of genetic details.
• Excellent reading and writing skills in medical language.
• Proficiency in Microsoft Office Suite (Excel, Word, PowerPoint, Outlook).
• Desired: Experience in bioinformatics analysis, variant effect prediction algorithms, and scripting languages.
• Desired: Familiarity with American College of Medical Genetics (ACMG) variant curation guidelines.
• Desired: Knowledge of copy number variation (CNV) concepts and genomic variation's correlation with human disease.

Competencies

Quality Assurance, Analytical, Problem Solving, Technical Skills, Interpersonal Skills, Oral and Written Communication, Teamwork, Organizational Support, Safety and Security, Dependability, Innovation, Adaptability.

Physical Demands And Work Environment

This role frequently requires sitting, standing, and the use of hands and fingers for dexterity. The position also involves frequent talking, hearing, and utilizing visual acuity for operating equipment, reading technical information, and keyboard use.

EEO Statement

Baylor Genetics is an equal opportunity employer committed to diversity and inclusion. We do not discriminate on any protected status.

Key skills/competency

• Molecular Genetics Analysis Assistant
• Quality Control
• Genomic Data Analysis
• HGVS Standards
• Variant Identity
• NGS Data
• Clinical Genomics
• Variant Curation
• Bioinformatics
• Pharmacogenomics