Principal Clinical Scientist
Alignerr · India
- Hybrid
- Contract
- $100,000 / year
- India
Job highlights
- Shape AI with clinical trial expertise.
- Ensure AI data meets regulatory standards.
- Design and review clinical trial protocols.
- Evaluate AI clinical analyses for soundness.
- Work remotely on frontier AI systems.
About the role
Principal Clinical Scientist (AI Training)
About The Role
What if your years of clinical trial expertise could directly shape how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to frontier AI research — ensuring the clinical data that trains and evaluates next-generation AI systems meets the standards expected in real-world regulatory environments.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want to contribute to something genuinely new. You don't need an AI background — just deep expertise in clinical trial design, regulatory data interpretation, and the scientific standards that matter most.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
- Provide expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Help set the standard for how clinical rigor is applied across AI-driven biomedical research workflows
Who You Are
- Senior-level experience designing clinical trial protocols for regulatory submission
- Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or international equivalents
- Strong command of clinical research methodology, biostatistics, or translational science
- Comfortable working independently and asynchronously — you know how to manage your own time and deliver high-quality work without hand-holding
- Sharp written communicator who can translate complex regulatory reasoning into clear, structured feedback
Nice to Have
- Prior experience with data annotation, data quality review, or AI evaluation workflows
- Background in pharmacovigilance, outcomes research, or evidence synthesis
- Familiarity with AI tools or clinical decision support systems as an end user
Why Join Us
- Work directly on frontier AI systems shaping the future of clinical and biomedical research
- Fully remote and flexible — structure your hours around your life, not the other way around
- Freelance autonomy with the substance of meaningful, expert-level work
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence at scale
- Collaborate with world-leading AI research teams on problems that genuinely matter
- Potential for ongoing work and contract extension as new projects launch
Key skills/competency
- Clinical Trial Design
- Regulatory Data Interpretation
- AI Training Data
- Clinical Research Methodology
- Biostatistics
- Translational Science
- FDA/EMA Regulations
- Data Quality Review
- AI Evaluation
- Biomedical Research
Skills & topics
- Principal Clinical Scientist
- Clinical Trial Design
- Regulatory Data Interpretation
- AI Training Data
- Clinical Research Methodology
- Biostatistics
- Translational Science
- FDA
- EMA
- Biomedical Research
- Remote
- Contract
- Hourly
- AI
- Healthcare AI
How to get hired
- Tailor your resume: Highlight clinical trial design and regulatory data interpretation experience for this Principal Clinical Scientist role.
- Showcase your impact: Quantify your experience in interpreting clinical data for FDA/EMA submissions.
- Demonstrate remote readiness: Emphasize your ability to work independently and asynchronously.
- Prepare for technical questions: Be ready to discuss clinical research methodology and biostatistics.
- Communicate clearly: Practice articulating complex regulatory reasoning concisely.
Technical preparation
Master clinical trial protocol design.,Deeply understand FDA/EMA data interpretation.,Review biostatistics and research methodology.,Prepare to evaluate AI analysis soundness.
Behavioral questions
Describe a complex regulatory submission challenge.,How do you ensure data accuracy and consistency?,Explain your asynchronous work management approach.,How do you provide constructive critical feedback?
Frequently asked questions
- What is the work arrangement for the Principal Clinical Scientist role at Alignerr?
- The Principal Clinical Scientist position at Alignerr is fully remote. This offers flexibility in how you structure your working hours to accommodate your life outside of work.
- Do I need prior AI experience to apply for the Principal Clinical Scientist job?
- No, an AI background is not required for the Principal Clinical Scientist role. Alignerr is looking for deep expertise in clinical trial design, regulatory data interpretation, and scientific standards.
- What are the primary responsibilities of a Principal Clinical Scientist at Alignerr?
- As a Principal Clinical Scientist, you will design and review clinical trial protocols for AI training data, interpret clinical trial results for regulatory relevance, evaluate AI-generated analyses, and provide expert feedback to improve AI models' reasoning about clinical data.
- What kind of commitment is expected for this Principal Clinical Scientist contract role?
- The commitment for this hourly contract role ranges from 10 to 40 hours per week, offering flexibility in workload depending on project needs and your availability.
- How does Alignerr ensure clinical rigor is applied to AI research?
- Alignerr applies clinical rigor by having experienced Principal Clinical Scientists like you design and review protocols, interpret results, and evaluate AI analyses to ensure alignment with regulatory expectations and scientific soundness.
- What is the significance of FDA/EMA regulatory expectations in this role?
- FDA, EMA, or equivalent regulatory expectations are crucial as the AI training data must meet the standards required for real-world regulatory environments. Your role involves ensuring AI-generated analyses align with these expectations.
- What are the 'nice to have' qualifications for the Principal Clinical Scientist role?
- Nice-to-have qualifications include prior experience with data annotation, data quality review, AI evaluation workflows, a background in pharmacovigilance or outcomes research, and familiarity with AI tools as an end user.