Statistician – Rare Diseases Ophthalmology

@ AAVantgarde

Company Overview

AAVantgarde is a clinical-stage, international biotechnology company headquartered in Italy. The company has developed two cutting-edge AAV vector platforms targeting Usher syndrome type 1B and Stargardt disease. Founded by Professor Alberto Auricchio, a gene therapy pioneer, their mission is to transform genetic medicine for patients with currently no therapeutic options.

Role Overview

The Statistician – Rare Diseases Ophthalmology will design, analyze, and report clinical trials in rare diseases with a strong focus on ophthalmology. The role involves drafting statistical analysis plans, performing sample size calculations, developing endpoint strategies, and generating outputs for study reports and regulatory filings.

• Provide statistical leadership in clinical trial studies.
• Work cross-functionally with teams on data integrity.
• Contribute to regulatory submissions and internal standards.
• Guide study design decisions and long-term methodologies.
• Mentor junior statisticians in a collaborative setting.

Skills & Experience

Ideal candidates will have an MSc or PhD in Statistics, Biostatistics or related, with 5-10 years of experience in clinical trial statistics. Proficiency in SAS and/or R is required, along with hands-on experience in rare-disease and ophthalmology studies. Familiarity with regulatory expectations and longitudinal data analysis is essential.

Equal Opportunities & Recruitment Policy

AAVantgarde promotes a welcoming, inclusive environment with equal opportunities for all candidates. All recruitment activities are managed by the HR team; unsolicited recruiter submissions will not be considered.

Key skills/competency

• Clinical Trials
• Data Analysis
• Statistical Analysis
• Regulatory Submissions
• Ophthalmology
• SAS
• R Programming
• Biostatistics
• Rare Diseases
• Study Design