Senior/Principal Scientist, Translational Biomarkers
NewLimit · South San Francisco
Posted about 3 months ago · $155,000 to $200,000
or apply directly on NewLimit's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 82 days NewLimit's roles stay open a median of 82 days
- Reposted
- No
- Salary listed
- Yes 82% of NewLimit's roles list one
- Ghost-job risk at NewLimit
- high 16 stale, 0 reposted of 17 open
- Hiring momentum
- 19 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-10-24
Measured from postings appearing on and disappearing from NewLimit's own greenhouse board since 2026-08-03. Full hiring picture for NewLimit.
About this role
The Principal/Senior Scientist will lead the discovery and development of pharmacodynamic biomarker assays to support the clinical development of mRNA-LNP medicines. This role involves designing and qualifying assays, defining advancement criteria, analyzing data, and mentoring team members within the bioanalytical function.
- benefits
- 3/5
- freshness
- 1/5
- career value
- 4/5
- role clarity
- 5/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of NewLimit as an employer.
What you need
- PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years)
- 3+ years of hands-on experience in various quantitative bioanalytical assay platforms (e.g., RT-qPCR, ddPCR, ELISA, MSD, Olink, SOMAscan, NGS-based methods) in complex biological matrices
- Strong working knowledge of bioanalytical method qualification/validation principles for PD biomarker measurements
- History of delivering results for bioanalytical projects
- Experience with primary cell culture and tissue-derived sample workflows
Nice to have
- Experience in bioanalytical method transfer and CRO management for outsourced discovery or assay qualification work
- Familiarity with preclinical drug development timelines and regulatory submissions (IND, TGA, CTD format)
- Experience in LNP-RNA biodistribution and PD assay development
- Experience developing products in emerging therapeutic modalities (gene therapy, nucleic acid therapies, cell therapy)
What you get
- Comprehensive Health, Dental, and Vision insurance
- 401(k) plan with company match
- Paid parental leave
- Industry-leading PTO: 20 days per year plus holidays
- On-site meals and snacks
Worth weighing
- Salary range provided is broad and depends on various factors
- Role involves significant technical leadership and mentoring responsibilities
- Focus on regulatory submissions may indicate a structured environment with potential for high accountability
Summarised from NewLimit's posting. Read the full original.
Listed by NewLimit on their greenhouse job board, last confirmed open on 2026-10-24. PitchMeAI is not the employer.
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