Principal Scientist, Process Chemistry
Calico · South San Francisco, CA
Posted about 2 months ago · $197,000 - $230,000 · Previously reposted
or apply directly on Calico 's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 55 days Calico 's roles stay open a median of 55 days
- Reposted
- Yes taken down and listed again at least once
- Salary listed
- Yes 83% of Calico 's roles list one
- Ghost-job risk at Calico
- high 15 stale, 2 reposted of 18 open
- Hiring momentum
- 23 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-09-27
Measured from postings appearing on and disappearing from Calico 's own greenhouse board since 2026-08-03. Full hiring picture for Calico .
About this role
The Principal Scientist, Process Chemistry role at Calico involves designing, optimizing, and executing synthetic processes for small-molecule intermediates and APIs. The position requires extensive hands-on experience in process research and scale-up, along with conducting laboratory experiments to enhance yields and control impurities. Collaboration with cross-functional teams and maintaining compliance with safety standards are also key aspects of the job.
- benefits
- 1/5
- freshness
- 5/5
- career value
- 4/5
- role clarity
- 5/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Calico as an employer.
What you need
- PhD in Organic Chemistry or related field
- 8+ years of relevant industrial experience in process chemistry
- Strong expertise in synthetic organic chemistry and reaction mechanism fundamentals
- Demonstrated success in developing scalable synthetic processes
- Proficiency with standard analytical instruments and data interpretation
- Excellent problem-solving, organization, and communication skills
What you get
- Estimated base salary range of $197,000 - $230,000
- Eligible for two annual cash bonuses
Worth weighing
- Role requires working onsite 5 days a week
- Salary range is provided but actual pay depends on experience and qualifications
Summarised from Calico 's posting. Read the full original.
Listed by Calico on their greenhouse job board, last confirmed open on 2026-09-27. PitchMeAI is not the employer.
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