or apply directly on Calico 's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 12 days Calico 's roles stay open a median of 81 days
- Reposted
- No
- Salary listed
- Yes 85% of Calico 's roles list one
- Ghost-job risk at Calico
- high 17 stale, 2 reposted of 20 open
- Hiring momentum
- 25 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-10-23
Measured from postings appearing on and disappearing from Calico 's own greenhouse board since 2026-08-03. Full hiring picture for Calico .
About this role
The Head of Medical Affairs at Calico will lead the medical affairs function, focusing on the launch of a therapy for Vanishing White Matter (VWM). This role involves developing and executing medical affairs strategies, building teams, and fostering relationships with key opinion leaders and patient advocacy organizations. The position requires collaboration across various departments to ensure compliance and effective communication of scientific data.
- benefits
- 1/5
- freshness
- 5/5
- career value
- 5/5
- role clarity
- 5/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Calico as an employer.
What you need
- Advanced degree required: MD or MD/PhD, PharmD, or PhD in a relevant scientific or clinical discipline
- 10+ years of pharmaceutical/biotech industry experience
- 5+ years leadership in medical affairs
- Demonstrated experience leading or building medical affairs functions in a launch setting
- Deep expertise launching first-in-disease therapies for rare genetic diseases
- Strong understanding of healthcare systems, compliance guidelines, and the distinct diagnostic and regulatory unique to rare diseases
Nice to have
- Prior experience in clinical practice
- Experience operating in US health care system, with knowledge of global/international markets also preferred
What you get
- Estimated base salary range of $310,000 - $420,000
- Eligible for two annual cash bonuses
Worth weighing
- Role involves significant responsibility in a launch setting, which may be high-pressure
- Complexity of the role requires strong leadership and communication skills
- No remote work flexibility beyond 1 day per week
- Travel requirements may impact work-life balance
Summarised from Calico 's posting. Read the full original.
Listed by Calico on their greenhouse job board, last confirmed open on 2026-10-23. PitchMeAI is not the employer.
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