Arc Institute

Senior Director, Disease Biology

Arc Institute · Palo Alto, CA

Posted 23 days ago · $263,500 to $325,500

or apply directly on Arc Institute's site. We never take the application ourselves.

Is this posting real?

This role has been open
23 days
Arc Institute's roles stay open a median of 45 days
Reposted
No
Salary listed
Yes
64% of Arc Institute's roles list one
Ghost-job risk at Arc Institute
high
15 stale, 0 reposted of 25 open
Hiring momentum
26 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-09-17

Measured from postings appearing on and disappearing from Arc Institute's own greenhouse board since 2026-08-03. Full hiring picture for Arc Institute.

About this role

The Senior Director of Disease Biology at Arc Institute will lead the Alzheimer's Disease Initiative, focusing on target discovery and preclinical development. This role involves building a new team, guiding drug discovery programs, and collaborating with various teams to validate therapeutic targets. The position requires a strategic approach to scientific innovation and a commitment to advancing understanding of Alzheimer's disease.

Our read on this posting4.0out of 5
benefits
1/5
freshness
4/5
career value
5/5
role clarity
5/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Arc Institute as an employer.

What you need

  • PhD in neuroscience, immunology, cell biology, genetics, pharmacology, or a related field
  • Extensive experience leading target discovery in neurodegeneration
  • Track record advancing programs from validated target through lead optimization
  • Deep expertise developing or applying advanced 3D cellular models of neurodegenerative disease
  • Proven people leadership, including mentoring and building teams
  • Strong partnership with computational biology and machine learning teams

Nice to have

  • Direct experience in Alzheimer's disease drug discovery
  • Hands-on experience generating and validating animal models of Alzheimer’s disease
  • Experience integrating computational and machine learning driven target prioritization into discovery strategy
  • Experience partnering with high throughput biology teams

What you get

  • Base salary range of $263,500 to $325,500
  • Eligible for an annual discretionary bonus based on performance

Worth weighing

  • The role requires a significant commitment to onsite work in Palo Alto
  • The salary range is provided, but actual compensation may vary based on several factors
  • The position involves high-risk, long-term research without commercial pressures, which may appeal to some candidates but not others

Summarised from Arc Institute's posting. Read the full original.

Listed by Arc Institute on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

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