In Vitro Neuroscientist
Astera · Emeryville HQ
- On site
- Fulltime
- Emeryville HQ
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Subject: Interested in the In Vitro Neuroscientist role at Astera
Hi Casey — I came across the In Vitro Neuroscientist opening and wanted to reach out directly. I've spent the last few years doing exactly this kind of work, and Astera stood out because…
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About the role
About Astera
Astera is a private foundation on a mission to steer science and technology toward an abundant future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to dramatically accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive scientific progress.
Unlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. You can read more about our mission, vision, and programming here.
Position Summary
The Astera Institute is seeking an exceptional experimental neuroscientist to develop and execute experiments using in vitro brain slice prep. This role will focus on functional characterization of complex neuronal networks using electrophysiology, imaging, and bioengineering approaches.
The ideal candidate is deeply experienced in neuronal cell culture and excited to work at the intersection of stem cell biology, neurotechnology, and quantitative neuroscience.
Responsibilities
Design and execute experiments using in vitro brain slice prep
Characterize neuronal network activity and circuit dynamics
Perform and optimize electrophysiological recordings, including patch clamp and multielectrode array (MEA) platforms
Implement optical and imaging-based methods for monitoring neuronal function, including calcium and voltage imaging
Contribute to experimental strategy, technology development, publications, and scientific direction in a fast-moving research environment
Maintain rigorous experimental documentation and data standards
Qualifications and Experience
PhD in Neuroscience, Neurobiology, Biomedical Engineering, Physiology, or related discipline
Strong track record of hands-on experimental neuroscience research
Expertise in one or more of the following:
Optical techniques for probing neural circuits
Patch clamp electrophysiology
Multielectrode array systems
Functional imaging of neuronal activity
Human stem cell-derived neural cultures or organoids
Neural signal analysis and quantitative neuroscience
Experience culturing and maintaining neuronal systems in vitro
Proficiency in data analysis using Python, MATLAB, or similar scientific computing tools
Location
This position is onsite at our office in Emeryville, CA. Some travel may be required from time-to-time for in-person collaboration and work.
Compensation
The posted salary range is based on location in the Bay Area. The successful candidate will receive a competitive compensation package, commensurate with their experience and location.
Cultural Alignment
Surprising problem-solver – you love finding unexpected solutions to problems we don't even know we have, and see options where others only see constraints.
Flexible by default – you don't draw hard lines around your job description and expect your role to evolve significantly over 6–12 months.
Bias to action – you launch and iterate on thoughtful experiments rather than waiting for perfect plans, and you're energized by novel problems.
High standards, internally driven – you believe you can build the world's best vehicle for unleashing extraordinary individuals to create public goods, and you hold yourself to that bar without benchmarking against others.
Open to feedback – You create opportunities to give and receive honest feedback, staying focused on both personal and team growth, and committing to transparency even when it’s uncomfortable.
Operate with the highest levels of integrity, judgment, and stewardship -- you treat residents, peers, and vendors with genuine respect for their time and contributions.
Embrace the tools that define great work today – Astera is building for an AI-driven future and equips the team accordingly. We see these as genuine force multipliers, not optional extras, and we expect our people to use them