Twist Bioscience

Senior Computational Scientist

Twist Bioscience · USA - South San Francisco, CA

Posted 14 days ago

or apply directly on Twist Bioscience's site. We never take the application ourselves.

Is this posting real?

This role has been open
14 days
Twist Bioscience's roles stay open a median of 45 days
Reposted
No
Salary listed
No
0% of Twist Bioscience's roles list one
Ghost-job risk at Twist Bioscience
high
19 stale, 1 reposted of 38 open
Hiring momentum
55 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-09-17

Measured from postings appearing on and disappearing from Twist Bioscience's own greenhouse board since 2026-08-03. Full hiring picture for Twist Bioscience.

About this role

The Senior Computational Scientist role at Twist involves developing AI and computational solutions for protein design and discovery. You will collaborate with various teams to create algorithms that integrate protein sequences with experimental data, lead the development of AI methods, and translate scientific needs into practical solutions. This position requires hands-on experience in computational biology and machine learning, particularly with protein language models.

Our read on this posting3.2out of 5
benefits
2/5
freshness
4/5
career value
5/5
role clarity
5/5
pay transparency
0/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Twist Bioscience as an employer.

What you need

  • Minimum of 5 years of industry experience with a PhD
  • PhD in computational biology, bioinformatics, machine learning, computer science, protein science, or a related field
  • Extensive experience developing algorithms for protein design, engineering, discovery, or sequence analysis
  • Demonstrated experience developing and applying AI/ML methods to proteins or other biological sequences
  • Strong understanding of protein language models (PLMs) and protein sequence-structure-function relationships
  • Experience analyzing NGS data from biological selection, screening, or related workflows

Nice to have

  • Experience with antibody discovery, engineering, or characterization
  • Experience with biopanning, display-based discovery, or other protein-selection platforms
  • Experience integrating protein sequence, NGS, and experimental assay data
  • Experience with generative protein design, property prediction, or candidate-ranking methods

What you get

  • Eligible for bonus
  • Equity
  • Generous benefits package

Worth weighing

  • No specific details on the benefits package provided
  • Base salary range provided is specific to the San Francisco Bay Area and may vary by location
  • Role involves a mix of research, software development, and troubleshooting, which may require flexibility

Summarised from Twist Bioscience's posting. Read the full original.

Listed by Twist Bioscience on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

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