Vice President, Clinical Development
Spyre Therapeutics · US- Remote
Posted about 2 months ago · $366,000 to $398,000
or apply directly on Spyre Therapeutics's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 64 days Spyre Therapeutics's roles stay open a median of 64 days
- Reposted
- No
- Salary listed
- Yes 100% of Spyre Therapeutics's roles list one
- Ghost-job risk at Spyre Therapeutics
- high 3 stale, 0 reposted of 4 open
- Hiring momentum
- 8 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-10-06
Measured from postings appearing on and disappearing from Spyre Therapeutics's own greenhouse board since 2026-08-03. Full hiring picture for Spyre Therapeutics.
About this role
The Vice President of Clinical Development at Spyre Therapeutics will lead the clinical strategy and execution for antibody therapeutics targeting inflammatory bowel disease (IBD). This role involves hands-on leadership in ongoing clinical trials, protocol development, and collaboration with cross-functional teams to ensure successful study execution and regulatory compliance. The ideal candidate will balance strategic oversight with direct involvement in clinical operations, contributing to the company's growth in a fast-paced biotech environment.
- benefits
- 3/5
- freshness
- 1/5
- career value
- 5/5
- role clarity
- 5/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Spyre Therapeutics as an employer.
What you need
- MD or equivalent medical degree
- Minimum of 7+ years clinical development experience within the pharmaceutical or biotech industry
- Substantial leadership experience in immunology, inflammation, or gastroenterology
- Demonstrated success leading mid- and late-stage clinical development programs
- Strong understanding of clinical trial design, biostatistics, translational medicine, drug development, and global regulatory requirements
- Demonstrated ability to influence strategy and drive cross-functional decision-making in a matrixed environment
Nice to have
- Training and/or experience in clinical development in gastroenterology or immunology & inflammation
- Experience developing antibody therapeutics
- Experience leading complex, adaptive, umbrella, basket, or platform clinical trials
- Deep expertise in inflammatory bowel disease and/or other immune-mediated inflammatory disorders
- Significant experience with global regulatory interactions and submissions, including INDs, CTAs, briefing documents for global regulatory agencies
What you get
- Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
- Unlimited PTO
- Two, one-week company-wide shutdowns each year
- Commitment to provide professional development opportunities
- Remote working environment with frequent in-person meetings
Worth weighing
- No specific details on the company's current pipeline or stage of development for the therapies mentioned
- The role requires balancing strategic leadership with hands-on execution, which may be demanding in a high-growth environment
- The expected salary range is provided, but actual pay may vary based on various factors
Summarised from Spyre Therapeutics's posting. Read the full original.
Listed by Spyre Therapeutics on their greenhouse job board, last confirmed open on 2026-10-06. PitchMeAI is not the employer.