Senior Director, Biostatistics
Spyre Therapeutics · US- Remote
Posted about 2 months ago · $ 275,000 to $290,000
or apply directly on Spyre Therapeutics's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 64 days Spyre Therapeutics's roles stay open a median of 64 days
- Reposted
- No
- Salary listed
- Yes 100% of Spyre Therapeutics's roles list one
- Ghost-job risk at Spyre Therapeutics
- high 3 stale, 0 reposted of 4 open
- Hiring momentum
- 8 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-10-06
Measured from postings appearing on and disappearing from Spyre Therapeutics's own greenhouse board since 2026-08-03. Full hiring picture for Spyre Therapeutics.
About this role
The Senior Director of Biostatistics will lead the biometrics team and provide strategic input for clinical development programs. Responsibilities include overseeing statistical activities for clinical trials, collaborating with cross-functional teams, managing biometrics vendors, and interacting with global health authorities. This role requires hands-on involvement in trial design, statistical analysis, and ensuring high-quality data management.
- benefits
- 4/5
- freshness
- 1/5
- career value
- 4/5
- role clarity
- 5/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Spyre Therapeutics as an employer.
What you need
- PhD Degree in Biostatistics, Statistics, or a related field
- 10-12 years of experience in biostatistics within the pharmaceutical, biotech, or CRO industry
- Strong knowledge of statistical methodologies and their application in clinical trials
- Experience with regulatory submissions and interactions with regulatory agencies
- Proficiency in statistical software (e.g., SAS, R) and data management systems
- Experience with CDSIC including SDTM, ADaM, CDASH
Nice to have
- Working knowledge of Bayesian methodology
- Successful track record of working independently in a matrixed organization
What you get
- Market competitive compensation and benefits package
- Base salary, performance bonus, equity grant opportunities
- Health, welfare & retirement benefits
- Unlimited PTO
- Two, one-week company-wide shutdowns each year
- Commitment to provide professional development opportunities
Worth weighing
- The expected salary range is provided, but actual pay may vary based on various factors
- The role involves frequent in-person meetings despite being remote
- The company is still young and shaping its culture, which may appeal to some candidates but could be a challenge for others
Summarised from Spyre Therapeutics's posting. Read the full original.
Listed by Spyre Therapeutics on their greenhouse job board, last confirmed open on 2026-10-06. PitchMeAI is not the employer.