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Profluent

Lead Scientist / Associate Director, Bioinformatics and Data Science

Profluent · Emeryville, California, United States; Hybrid (2-3 days on-site)

Posted about 2 months ago

or apply directly on Profluent's site. We never take the application ourselves.

Is this posting real?

This role has been open
63 days
Profluent's roles stay open a median of 63 days
Reposted
No
Salary listed
No
0% of Profluent's roles list one
Ghost-job risk at Profluent
high
12 stale, 0 reposted of 12 open
Hiring momentum
17 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-10-05

Measured from postings appearing on and disappearing from Profluent's own greenhouse board since 2026-08-03. Full hiring picture for Profluent.

About this role

In this role, you will lead the development and operation of Profluent's NGS analysis platform, focusing on gene editing, protein design, and therapeutic programs. You will collaborate with wet-lab teams, establish rigorous practices in bioinformatics, and mentor a growing team. Your work will involve translating large-scale sequencing data into actionable biological insights and ensuring the scalability and reproducibility of computational workflows.

Our read on this posting2.8out of 5
benefits
3/5
freshness
1/5
career value
5/5
role clarity
5/5
pay transparency
0/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Profluent as an employer.

What you need

  • PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field
  • PhD with 5+ years or MS with 7+ years of industry experience applying NGS and computational analysis to gene or cell therapy development
  • Deep expertise in the design, analysis, and interpretation of high-throughput sequencing assays
  • Strong programming and quantitative analysis skills, particularly in Python
  • Proven ability to translate complex sequencing data into clear biological insights and program decisions
  • Experience partnering closely with experimental scientists to guide assay design, troubleshoot results, and define follow-up studies

Nice to have

  • Experience with CRISPR-based gene editing data and analysis
  • Familiarity with SQL and data modeling for biological or experimental data
  • Experience with LIMS platforms (e.g., Benchling) and lab data integration
  • Track record of developing production-quality scientific software and tools

What you get

  • High-growth opportunity with meaningful impact on the future of protein design
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Worth weighing

  • No remote work option mentioned, as the role requires 2-3 days on-site
  • Work authorization in the U.S. is required without employer sponsorship
  • The salary range is provided, which may help in evaluating the compensation package

Summarised from Profluent's posting. Read the full original.

Listed by Profluent on their greenhouse job board, last confirmed open on 2026-10-05. PitchMeAI is not the employer.

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