Maze Therapeutics

Manager, Chemical Development

Maze Therapeutics · South San Francisco, CA

Posted 19 days ago · $158,000 - $193,000

or apply directly on Maze Therapeutics's site. We never take the application ourselves.

Is this posting real?

This role has been open
19 days
Maze Therapeutics's roles stay open a median of 34 days
Reposted
No
Salary listed
Yes
100% of Maze Therapeutics's roles list one
Ghost-job risk at Maze Therapeutics
moderate
3 stale, 0 reposted of 14 open
Hiring momentum
18 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-09-17

Measured from postings appearing on and disappearing from Maze Therapeutics's own greenhouse board since 2026-08-03. Full hiring picture for Maze Therapeutics.

About this role

As the Manager of Chemical Development at Maze Therapeutics, you will oversee external contract manufacturing organizations (CMOs) involved in the production of drug substances for clinical programs. Your role includes optimizing chemical manufacturing processes, ensuring compliance with regulatory standards, and collaborating with various teams to facilitate the transition from preclinical to manufacturing stages. You will also prepare technical reports and analyze production methods to enhance efficiency, while managing multiple projects and maintaining audit readiness.

Our read on this posting4.2out of 5
benefits
3/5
freshness
4/5
career value
4/5
role clarity
5/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Maze Therapeutics as an employer.

What you need

  • M.S. or Ph.D. in synthetic organic chemistry
  • Postgraduate experience in process chemistry and/or cGMP chemical manufacturing (2-3 years for Ph.D., 5+ years for M.S.)
  • Working knowledge of chemical reaction mechanisms and kinetics
  • Experience with process optimization and scale-up
  • Familiarity with cGMP regulatory compliance in chemical manufacturing
  • Experience preparing technical reports and presenting findings

Nice to have

  • Experience working directly with external CMOs on technology transfer or scale-up
  • Background in environmental health and safety practices in a laboratory or manufacturing setting

What you get

  • Competitive medical, dental, and vision insurance
  • Mental health offerings
  • Equity incentive plan
  • 401(k) program with employer match
  • Generous holiday and PTO policy
  • Annual performance bonus

Worth weighing

  • Meetings outside standard business hours may be required due to international collaboration
  • Domestic and international travel will be necessary based on program and CMO needs

Summarised from Maze Therapeutics's posting. Read the full original.

Listed by Maze Therapeutics on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

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