Staff Software Engineer | Core Platform
Manifold AI · Cambridge, MA
Posted 8 days ago · $170,000–$220,000
or apply directly on Manifold AI's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 8 days Manifold AI's roles stay open a median of 43 days
- Reposted
- No
- Salary listed
- Yes 100% of Manifold AI's roles list one
- Ghost-job risk at Manifold AI
- high 2 stale, 0 reposted of 4 open
- Hiring momentum
- 5 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-09-17
Measured from postings appearing on and disappearing from Manifold AI's own greenhouse board since 2026-08-03. Full hiring picture for Manifold AI.
About this role
As a Staff Software Engineer on the Core Platform team at Manifold, you will design and operate compute infrastructure and workflow orchestration services that support enterprise users in analyzing genomics and life sciences datasets. This hands-on role involves mentoring engineers, improving service reliability, and translating customer requirements into platform capabilities, all while contributing to the company's AI-native vision in life sciences.
- benefits
- 1/5
- freshness
- 5/5
- career value
- 4/5
- role clarity
- 4/5
- pay transparency
- 5/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Manifold AI as an employer.
What you need
- 8+ years of enterprise software experience, particularly in backend, infrastructure-adjacent, or distributed systems work
- Mastery of Python and deep infrastructure-as-code experience with Terraform
- Experience managing compute environments on AWS including autoscaling and cost/performance tradeoffs
- Operational ownership mindset with a focus on observability and production outcomes
- Experience integrating AI tools into engineering workflows
- Strong understanding of the life sciences mission and its importance
Nice to have
- Bioinformatics workflow experience (WDL, Nextflow, or Cromwell)
- General life sciences or regulated-industry experience
What you get
- Strong compensation packages
- Excellent benefits
Worth weighing
- Salary range provided is $170,000–$220,000, but final offers may vary based on experience
- Role involves significant responsibility and ownership, which may not suit all candidates
- The position requires a proactive approach to operational standards and reliability
Summarised from Manifold AI's posting. Read the full original.
Listed by Manifold AI on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.