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Flagship Pioneering, Inc.

Senior Scientist, Protein Engineering

Flagship Pioneering, Inc. · Cambridge, MA USA

Posted 8 days ago · $126,000 - $181,500

or apply directly on Flagship Pioneering, Inc.'s site. We never take the application ourselves.

Is this posting real?

This role has been open
8 days
Flagship Pioneering, Inc.'s roles stay open a median of 45 days
Reposted
No
Salary listed
Yes
89% of Flagship Pioneering, Inc.'s roles list one
Ghost-job risk at Flagship Pioneering, Inc.
high
50 stale, 1 reposted of 100 open
Hiring momentum
144 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-09-17

Measured from postings appearing on and disappearing from Flagship Pioneering, Inc.'s own greenhouse board since 2026-08-03. Full hiring picture for Flagship Pioneering, Inc..

About this role

As a Senior Scientist at FL129, you will play a key role in developing a novel platform technology for small molecule drug discovery. Your responsibilities will include designing and constructing large-scale protein variant libraries, optimizing workflows, and translating experimental data into insights. This hands-on position offers substantial ownership and the opportunity to influence the scientific direction of the company from the outset.

Our read on this posting4.4out of 5
benefits
3/5
freshness
5/5
career value
5/5
role clarity
4/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Flagship Pioneering, Inc. as an employer.

What you need

  • Ph.D. in molecular biology, biochemistry, protein engineering, or a similar field
  • 5+ years of industry or postdoctoral experience
  • Strong track record of scientific and technical innovation in protein variant libraries
  • Deep experience with protein display systems, high-throughput sorting, and sequencing-based readouts
  • Experience with deep mutational scanning or related library-scale mutagenesis methods
  • Hands-on expertise in library-scale molecular cloning and managing library complexity

Nice to have

  • Experience with machine learning methods for protein engineering
  • Experience with statistical analysis of variant fitness landscapes

What you get

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Weekly lunches
  • Monthly social events
  • Community lunchroom with free snacks and coffee

Worth weighing

  • No specific technologies or tools mentioned, which may affect clarity on the tech stack
  • Role is among the first hires, indicating a startup environment with potential uncertainty

Summarised from Flagship Pioneering, Inc.'s posting. Read the full original.

Listed by Flagship Pioneering, Inc. on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

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