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Flagship Pioneering, Inc.

Senior Scientist, Protein Engineering

Flagship Pioneering, Inc. · Cambridge, MA USA

Posted about a month ago · $126,000 - $181,500

or apply directly on Flagship Pioneering, Inc.'s site. We never take the application ourselves.

Is this posting real?

This role has been open
43 days
Flagship Pioneering, Inc.'s roles stay open a median of 80 days
Reposted
No
Salary listed
Yes
89% of Flagship Pioneering, Inc.'s roles list one
Ghost-job risk at Flagship Pioneering, Inc.
high
97 stale, 1 reposted of 100 open
Hiring momentum
144 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-10-22

Measured from postings appearing on and disappearing from Flagship Pioneering, Inc.'s own greenhouse board since 2026-08-03. Full hiring picture for Flagship Pioneering, Inc..

About this role

As a Senior Scientist at FL129, you will play a key role in developing a novel platform technology for small molecule drug discovery. Your responsibilities will include designing and constructing large-scale protein variant libraries, optimizing workflows, and translating experimental data into insights. This hands-on position offers substantial ownership and the opportunity to influence the scientific direction of the company from the outset.

Our read on this posting4.4out of 5
benefits
3/5
freshness
5/5
career value
5/5
role clarity
4/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Flagship Pioneering, Inc. as an employer.

What you need

  • Ph.D. in molecular biology, biochemistry, protein engineering, or a similar field
  • 5+ years of industry or postdoctoral experience
  • Strong track record of scientific and technical innovation in protein variant libraries
  • Deep experience with protein display systems, high-throughput sorting, and sequencing-based readouts
  • Experience with deep mutational scanning or related library-scale mutagenesis methods
  • Hands-on expertise in library-scale molecular cloning and managing library complexity

Nice to have

  • Experience with machine learning methods for protein engineering
  • Experience with statistical analysis of variant fitness landscapes

What you get

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Weekly lunches
  • Monthly social events
  • Community lunchroom with free snacks and coffee

Worth weighing

  • No specific technologies or tools mentioned, which may affect clarity on the tech stack
  • Role is among the first hires, indicating a startup environment with potential uncertainty

Summarised from Flagship Pioneering, Inc.'s posting. Read the full original.

Listed by Flagship Pioneering, Inc. on their greenhouse job board, last confirmed open on 2026-10-22. PitchMeAI is not the employer.

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