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Flagship Pioneering, Inc.

Senior / Principal Scientist - Translational Modeling & Decision Science

Flagship Pioneering, Inc. · Cambridge, MA USA

Posted about 3 months ago · $146,000 - $236,000

or apply directly on Flagship Pioneering, Inc.'s site. We never take the application ourselves.

Is this posting real?

This role has been open
80 days
Flagship Pioneering, Inc.'s roles stay open a median of 80 days
Reposted
No
Salary listed
Yes
89% of Flagship Pioneering, Inc.'s roles list one
Ghost-job risk at Flagship Pioneering, Inc.
high
97 stale, 1 reposted of 100 open
Hiring momentum
144 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-10-22

Measured from postings appearing on and disappearing from Flagship Pioneering, Inc.'s own greenhouse board since 2026-08-03. Full hiring picture for Flagship Pioneering, Inc..

About this role

The (Senior) Scientist in Translational Modeling & Decision Science will leverage AI technologies to enhance decision-making in drug development across Flagship's therapeutic portfolio. This role involves producing quantitative analyses, translating scientific complexities into actionable recommendations, and collaborating with various teams to improve the AI platform based on field discoveries. The successful candidate will also be responsible for maintaining scientific standards and communicating results effectively within the organization.

Our read on this posting3.4out of 5
benefits
2/5
freshness
1/5
career value
4/5
role clarity
5/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Flagship Pioneering, Inc. as an employer.

What you need

  • PhD in a life sciences discipline with quantitative experience, or in a quantitative life sciences discipline with 3 to 7 years of industry experience
  • Strong knowledge of physiology, molecular biology, and immunology
  • Demonstrated expertise building mechanistic models for drug development decisions across multiple therapeutic areas
  • Ability to translate scientific complexity into recommendations for non-technical decision-makers
  • Excellent communication skills and composure under pressure
  • Proficiency in Python scientific computing (scipy, numpy, pandas) and numerical ODE integration

Nice to have

  • Experience applying frontier AI and LLM tools to drug development decisions
  • Translational breadth across drug modalities (small molecule, biologic, gene therapy, novel platforms)
  • Familiarity with regulatory credibility frameworks (ICH M15, FDA MIDD) and their application to internal decision-making
  • Experience in venture-backed or platform-company environments where analysis supports investment decisions

What you get

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits

Worth weighing

  • Salary range is $115,000 - $205,000, which may vary based on qualifications and experience
  • Role involves high-stakes decision-making with significant responsibility
  • Position requires collaboration across multiple programs, which may lead to a dynamic but potentially high-pressure environment

Summarised from Flagship Pioneering, Inc.'s posting. Read the full original.

Listed by Flagship Pioneering, Inc. on their greenhouse job board, last confirmed open on 2026-10-22. PitchMeAI is not the employer.

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