Amylyx Pharmaceuticals

Senior Director, Toxicology

Amylyx Pharmaceuticals · Cambridge, MA

Posted about 3 months ago

or apply directly on Amylyx Pharmaceuticals's site. We never take the application ourselves.

Is this posting real?

This role has been open
81 days
Amylyx Pharmaceuticals's roles stay open a median of 82 days
Reposted
No
Salary listed
No
0% of Amylyx Pharmaceuticals's roles list one
Ghost-job risk at Amylyx Pharmaceuticals
high
29 stale, 3 reposted of 29 open
Hiring momentum
42 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-10-24

Measured from postings appearing on and disappearing from Amylyx Pharmaceuticals's own greenhouse board since 2026-08-03. Full hiring picture for Amylyx Pharmaceuticals.

About this role

The Senior Director of Toxicology at Amylyx will lead the development and execution of nonclinical safety programs to support drug candidates from IND-enabling studies to market authorization. This role involves collaborating with cross-functional teams, mentoring scientific talent, and ensuring alignment with regulatory expectations while driving innovative safety assessment strategies. The position requires a strong background in toxicology and the ability to interpret complex data to inform development decisions.

Our read on this posting2.2out of 5
benefits
1/5
freshness
1/5
career value
4/5
role clarity
5/5
pay transparency
0/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Amylyx Pharmaceuticals as an employer.

What you need

  • PhD in Toxicology, Pharmacology, Molecular or Cell Biology, or a related science
  • Minimum experience of 10-12 years industry experience in toxicology and nonclinical drug development following completion of PhD or post doc
  • Demonstrated experience developing and executing nonclinical safety strategies to support drug discovery, candidate selection, IND-enabling studies, regulatory submissions, and clinical development
  • Broad knowledge in field of toxicology, with practical knowledge of pharmaceutical toxicology
  • Expert-level knowledge of global preclinical and clinical regulatory guidelines
  • Demonstrated ability to interpret complex toxicology and nonclinical data and translate findings into actionable development strategies

Nice to have

  • DABT certification is desirable
  • Direct experience with targeted delivery approach, rare disease development, endocrine and/or neuromuscular indication is desirable

Worth weighing

  • Remote work opportunities available, but not for applicants from certain states (Alaska, Arizona, Hawaii, Michigan, Tennessee)
  • Expected travel to the corporate location in Cambridge, MA several times a year
  • Compensation range provided, but final offer may vary based on experience and qualifications

Summarised from Amylyx Pharmaceuticals's posting. Read the full original.

Listed by Amylyx Pharmaceuticals on their greenhouse job board, last confirmed open on 2026-10-24. PitchMeAI is not the employer.

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