
Principal Solutions Architect | Lab Orchestration
Dotmatics · United States
- Hybrid
- Full-time
- $150,000 / year
- United States
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Subject: Interested in the Principal Solutions Architect | Lab Orchestration role at Dotmatics
Hi Jamie — I came across the Principal Solutions Architect | Lab Orchestration opening and wanted to reach out directly. I've spent the last few years doing exactly this kind of work, and Dotmatics stood out because…
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Job highlights
- Define end-to-end lab orchestration architectures.
- Bridge digital and physical lab environments.
- Design integration patterns for lab automation.
- Lead technical architecture for Luma solutions.
- Collaborate with customers and partners.
About the role
About Dotmatics
At Dotmatics, we believe science, data, and decision-making must be deeply intertwined for innovation to thrive. Our portfolio includes Luma, LumaLab Connect, ELN Platform, Graphpad Prism, Geneious, SnapGene, Protein Metrics, OMIQ, FCS Express, LabArchives, NQuery, EasyPanel, MStar, SoftGenetics, and Virscidian. We have a vision for a new Lab of the Future that will change the future of scientific research. We have created the world’s most comprehensive digital science platform – best-of-breed software applications already used by more than 2 million scientists, together in a single ecosystem united by a powerful, flexible enterprise data platform. This is not flat data buried away in digital graveyards. This is dynamic, multi-dimensional decision-making. Scientific enterprises need a new level of effectiveness to achieve tomorrow’s breakthroughs. Illness will not wait. The biosphere will not wait. We are tireless in our vision, because the time for innovation is now. Shaping the Future of Science At Dotmatics Our global team of more than 800 colleagues are dedicated to supporting our customers in over 180 countries. Together, with our scientific community of users, we accelerate scientific innovation in order to make the world a healthier, cleaner, and safer place to live. You’ll join a collaborative, global team pushing the boundaries of scientific innovation. Your ideas and efforts will have a tangible impact, accelerating scientific progress and discovery. We offer a dynamic, remote-friendly environment that fosters high integrity and collaboration, empowering you to excel. Dotmatics is a company built by scientists, for scientists. Combined, we are now the world’s largest cloud-based scientific research R&D platform. We need your help to keep growing and pioneering the future. We are Science Driven. We are Customer Centric. We are Better Together.
What We Need
We are seeking a Solutions Architect to be a senior technical authority within Dotmatics Professional Services, responsible for defining and governing end-to-end solution architectures, including its role as the orchestration backbone connecting scientific informatics, data pipelines, and physical lab execution environments. You will ensure that solutions are not only functionally correct, but also meet rigorous non-functional requirements around performance, scalability, security, reliability, observability, maintainability, and long-term operability.
In this role you will get to
Architecture & Design Authority
- Act as the design authority for Luma-based customer solutions, including end-to-end lab orchestration architectures that span scientific informatics, data infrastructure, and physical lab systems.
- Define logical and physical architectures covering applications, data, integrations, identity, environments, and operations.
- Architect solutions that bridge the digital and physical lab — connecting experiment planning, protocol authoring, and scheduling through to execution on automated instruments, workcells, and robotic platforms.
- Ensure architectural consistency across multiple customer engagements.
Functional & Non-Functional Requirements
- Shape functional requirements in collaboration with Scientific Architect and Application Scientists, including workflow automation requirements that span study design through instrument-level execution.
- Own non-functional requirements including performance, scalability, security, resilience, observability, accessibility, internationalisation, and maintainability.
- Translate business and scientific needs into robust technical architectures.
Integration, Data Architecture & Lab Orchestration
- Design integration approaches using technologies such as Apache NiFi, APIs, batch pipelines, and event-driven patterns.
- Define data ingestion, transformation, and migration strategies that accommodate the high-frequency, heterogeneous data generated by automated lab environments.
- Architect solutions that enable experiments to transition seamlessly from planned → scheduled → executing → data captured with minimal manual intervention, leveraging Luma as the orchestration layer.
- Define integration patterns with lab automation and scheduling platforms.
- Architect solutions leveraging Databricks, including configuration via Databricks SQL, for aggregation and analysis of instrument and experimental data at scale.
- Ensure data lineage, auditability, and regulatory compliance across the full experimental data lifecycle, from instrument output through to structured scientific records.
- Support visualisation and analytics patterns using tools such as Sigma for Databricks.
Platform and Enterprise Integration
- Architect Luma solutions that integrate with customer enterprise systems including: ELNs (Dotmatics & third-party), LIMS, SDMS, PLM, ERP, MES, instrument data systems, and lab automation schedulers.
- Define how Dotmatics fits within broader Siemens landscapes, particularly in environments where scientific R&D and industrial/manufacturing processes converge.
- Scope and design integrations with third-party scientific platforms including ELN/LIMS providers scientific data analysis tools (e.g., Spotfire, JMP, Pipeline Pilot, Geneious), and lab automation platforms.
- Define sample tracking, workcell scheduling, and instrument connectivity architectures as part of broader lab orchestration solution design.
Security, Reliability, and Operations
- Apply security best practices covering IAM, data protection, tenancy, and compliance.
- Design for high availability, resilience, and disaster recovery.
- Define observability strategies including logging, monitoring, and alerting — extended to cover automated lab execution environments and instrument connectivity layers.
- Ensure architectures are operable by support and cloud teams post go-live.
Stakeholder Engagement
- Act as senior technical advisor to customers, including IT leadership, enterprise architects, and lab automation/informatics leads.
- Partner with Sales and PreSales during solution shaping, scoping, and risk assessment — including technical qualification of lab orchestration opportunities.
- Represent Dotmatics architecture in joint Siemens engagements and architecture forums.
- Work with Siemens and non-Siemens partners as a peer architect ensuring architectural alignment across joint delivery models.
Technical Leadership & Enablement
- Provide architectural guidance to other Solution Architects, Technical Leads, Application Scientists, and Delivery Partners on lab orchestration patterns and integration architectures.
- Review designs and implementations for architectural compliance.
- Raise the overall architectural maturity of the Dotmatics Professional Services organisation and partner ecosystems, including in the emerging discipline of connected and automated lab design.
- Create reusable architectural artefacts including reference architectures, lab orchestration integration templates, instrument connectivity patterns, and design decision frameworks.
Partner Enablement
- Act as the architectural authority for partner-led implementations of the Dotmatics Luma platform.
- Enable system integrators, Siemens partners, and regional delivery partners through architectural guidance, design reviews, and technical enablement sessions.
- Define reference architectures, integration patterns, and implementation guardrails for partners — including guardrails for digital-physical integration scope and instrument connectivity standards.
- Support partner onboarding by defining "how Luma should be implemented" from an architectural and non-functional perspective.
- Ensure partner-delivered solutions meet Dotmatics and Siemens standards for scalability, security, operability, and maintainability.
- Collaborate with Partner, Sales, and Services leadership to define where Dotmatics retains architectural ownership.
- Act as an escalation point for complex architectural issues arising in partner-led engagements.
Qualifications
We are looking for people who have 10+ years with scoping automated scientific workflow-based solutions, designing enterprise-grade SaaS or hybrid architectures, ideally including experience with scientific informatics, lab automation, or connected laboratory environments. You may hold a Degree in Computer Science, Engineering, or a related technical or scientific field, and advanced understanding of integration patterns, APIs, data pipelines, and distributed systems — including event-driven architectures suitable for real-time instrument and automation data.
Key Skills We are looking for
- Technical Architecture: Experience with data platforms (Databricks) and integration tools (Apache NiFi). Ability to reason about performance, scalability, and failure modes across heterogeneous, multi-system environments. Familiarity with lab automation connectivity standards and protocols (SiLA2, LADS, OPC-UA) and their architectural implications.
- Enterprise & Lab Systems Exposure: Experience integrating complex application landscapes (ELN, LIMS, SDMS, PLM, ERP, MES, instrument data systems, lab automation schedulers) across heterogeneous customer IT and OT environments. Understanding of how digital workflow systems connect to physical lab execution.
- Scientific Domain Appreciation: Scientific R&D workflows and data, particularly in life sciences, pharma/biotech, or regulated lab environments. Appreciation of the practical realities of laboratory automation — what it means for an experiment to go from planned to actually running on an instrument.
- Leadership & Communication: Able to explain complex architectural decisions — including digital-physical integration trade-offs — to scientific, IT, and operational audiences.
- Partner and Ecosystem Experience: Experience working with system integrators or technology partners in enterprise delivery models. Comfortable defining guardrails rather than prescribing every implementation detail. Able to balance enablement with governance in partner-led engagements.
Skills & topics
- Solutions Architect
- Lab Orchestration
- Scientific Informatics
- Data Architecture
- Integration
- Databricks
- Apache NiFi
- SaaS
- Cloud
- R&D
- Life Sciences
- Pharma
- Biotech
- Lab Automation
- Connected Lab
- Enterprise Architecture
- Scalability
- Security
- Reliability
- Observability
- Technical Leadership
How to get hired
- Tailor your resume: Highlight experience in scientific informatics, lab automation, and enterprise SaaS architecture. Quantify achievements in scoping and designing complex solutions.
- Craft a compelling cover letter: Emphasize your leadership in technical architecture and stakeholder engagement, aligning your skills with Dotmatics' vision for the Lab of the Future.
- Prepare for technical deep dives: Be ready to discuss your experience with Databricks, Apache NiFi, integration patterns, and lab automation connectivity standards.
- Showcase collaboration skills: Demonstrate your ability to advise customers and partners, and to elevate architectural maturity within an organization.
- Research Dotmatics: Understand their comprehensive digital science platform and how your role contributes to accelerating scientific innovation.
Technical preparation
Behavioral questions
Frequently asked questions
- What are the key technical skills required for the Principal Solutions Architect role at Dotmatics?
- The Principal Solutions Architect role at Dotmatics requires strong technical architecture skills, including experience with data platforms like Databricks and integration tools like Apache NiFi. Familiarity with lab automation connectivity standards (SiLA2, LADS, OPC-UA) and a deep understanding of integrating complex enterprise systems (ELN, LIMS, SDMS, etc.) are crucial. You should also have advanced knowledge of integration patterns, APIs, data pipelines, and distributed systems.
- What kind of scientific domain experience is beneficial for this position?
- While not strictly mandatory, an appreciation for scientific R&D workflows and data, particularly in life sciences, pharma/biotech, or regulated lab environments, is highly beneficial. Understanding the practicalities of laboratory automation, from experiment planning to instrument execution, will enable you to architect more effective solutions.
- How does Dotmatics support remote work for this Principal Solutions Architect position?
- Dotmatics offers a dynamic, remote-friendly environment. While the specific details of remote work arrangements would be discussed during the hiring process, the company culture is designed to empower employees to excel regardless of their physical location, fostering high integrity and collaboration.
- What is the expected experience level for the Principal Solutions Architect?
- Dotmatics is looking for candidates with over 10 years of experience. This should include scoping automated scientific workflow-based solutions and designing enterprise-grade SaaS or hybrid architectures, with a strong preference for experience in scientific informatics, lab automation, or connected laboratory environments.
- Can you explain the 'Lab of the Future' vision at Dotmatics?
- The 'Lab of the Future' vision at Dotmatics involves creating a comprehensive digital science platform that deeply intertwines science, data, and decision-making. This platform aims to accelerate scientific innovation by connecting best-of-breed software applications within a unified ecosystem, enabling dynamic, multi-dimensional decision-making for scientific enterprises.
- What role does Luma play in the solutions designed by this architect?
- Luma serves as the central orchestration layer in the solutions designed by the Principal Solutions Architect. The architect will be responsible for defining Luma-based customer solutions, including end-to-end lab orchestration architectures that span scientific informatics, data infrastructure, and physical lab systems, ensuring seamless transitions from experiment planning to data capture.
