Septerna

Director, Program and Portfolio Management

Septerna · South San Francisco, California, United States

Posted about 2 months ago · $230,000 - $255,000

or apply directly on Septerna's site. We never take the application ourselves.

Is this posting real?

This role has been open
66 days
Septerna's roles stay open a median of 66 days
Reposted
No
Salary listed
Yes
67% of Septerna's roles list one
Ghost-job risk at Septerna
high
3 stale, 0 reposted of 3 open
Hiring momentum
5 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-10-08

Measured from postings appearing on and disappearing from Septerna's own greenhouse board since 2026-08-03. Full hiring picture for Septerna.

About this role

The Director of Program and Portfolio Management at Septerna will lead program management for development programs from preclinical stages through clinical development. This role involves creating integrated program plans, managing risks, and ensuring effective communication among stakeholders. The position requires collaboration with cross-functional teams to align program execution with company strategy and to drive decision-making processes.

Our read on this posting3.2out of 5
benefits
1/5
freshness
1/5
career value
4/5
role clarity
5/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Septerna as an employer.

What you need

  • Advanced degree relevant to drug discovery/development; Ph.D./PharmD/MBA preferred
  • Minimum of at least 10-15+ years of experience within the Biotech or Pharma industry
  • Prior experience in project management, specifically in the clinical development space
  • Proven expertise in project planning, execution, and risk management
  • Deep understanding of drug development processes, particularly in endocrinology, immunology, CNS
  • Demonstrated track record of managing small molecule discovery projects from early research through development candidates and IND/CTA submissions

What you get

  • Compensation package includes benefits, stock options, and annual target bonus for full-time positions

Worth weighing

  • Position requires in-person collaboration with cross-functional teams
  • No specific mention of remote work options
  • Salary range provided, but individual pay may vary based on factors like skills and experience

Summarised from Septerna's posting. Read the full original.

Listed by Septerna on their greenhouse job board, last confirmed open on 2026-10-08. PitchMeAI is not the employer.

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