Personalis, Inc

Sr. Software Engineer, Clinical Software

Personalis, Inc · Fremont, CA

Posted 28 days ago · $150,000 to $175,000

or apply directly on Personalis, Inc's site. We never take the application ourselves.

Is this posting real?

This role has been open
28 days
Personalis, Inc's roles stay open a median of 31 days
Reposted
No
Salary listed
Yes
93% of Personalis, Inc's roles list one
Ghost-job risk at Personalis, Inc
moderate
5 stale, 0 reposted of 15 open
Hiring momentum
26 roles opened in the last 90 days
↑ up vs. the prior 90 days
Last confirmed on the employer's board
2026-09-17

Measured from postings appearing on and disappearing from Personalis, Inc's own greenhouse board since 2026-08-03. Full hiring picture for Personalis, Inc.

About this role

The Sr. Software Engineer will design, develop, and maintain Laboratory Information Management Systems (LIMS) at Personalis. This role involves developing backend services and APIs, deploying solutions in AWS, and collaborating with cross-functional teams to translate business requirements into technical solutions. The engineer will also participate in code reviews and troubleshoot complex technical issues in a regulated environment.

Our read on this posting4.4out of 5
benefits
5/5
freshness
4/5
career value
4/5
role clarity
4/5
pay transparency
5/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Personalis, Inc as an employer.

What you need

  • B.S. degree in Computer Science, Engineering, or a related technical field
  • 5 years of professional software development experience
  • Strong proficiency in at least one programming language such as Python or Java
  • Proven experience building and deploying applications on AWS
  • Solid experience with relational databases (e.g., PostgreSQL, MySQL) and developing REST APIs
  • Experience with version control systems (e.g., Github, Bitbucket) and CI/CD concepts

Nice to have

  • Experience with web frameworks like Flask or FastAPI
  • Familiarity with modern JavaScript frameworks (e.g., React, Angular, or Vue.js)
  • Experience in the life sciences, healthcare, or another regulated industry
  • Familiarity with containerization technologies (e.g., Docker)
  • Exposure to graph databases or NoSQL technologies

What you get

  • Annual performance-based bonus
  • Long-term incentive units (equity)
  • Full range of medical, dental, vision benefits
  • 401(k) match
  • Employee Stock Purchase Plan (ESPP)
  • Tuition reimbursement

Worth weighing

  • Onsite work required three days a week (Monday, Tuesday, Thursday)
  • Role involves working in a regulated environment which may have strict compliance requirements
  • No specific mention of remote work flexibility beyond the hybrid model

Summarised from Personalis, Inc's posting. Read the full original.

Listed by Personalis, Inc on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

More roles at Personalis, Inc

All 15 open roles at Personalis, Inc

Apply to a Sr. Software Engineer, Clinical Software position at Personalis, Inc - Jobs near me at Fremont, CA