Sr. Scientist, Lentivirus Upstream Processing

Legend Biotech US · Somerset, New Jersey, United States

Posted 15 days ago

or apply directly on Legend Biotech US's site. We never take the application ourselves.

Is this posting real?

This role has been open: 15 days
Reposted: No
Salary listed: No
Ghost-job risk at Legend Biotech US: high
Hiring momentum: 125 roles opened in the last 90 days
Last confirmed on the employer's board: 2026-09-17

Measured from postings appearing on and disappearing from Legend Biotech US's own greenhouse board since 2026-08-03. Full hiring picture for Legend Biotech US.

About this role

The Sr. Scientist, Lentivirus Upstream Processing will be a key contributor in the Technical Development team, focusing on designing and optimizing upstream production processes for lentiviral vectors. Daily responsibilities include executing experimental strategies, supporting GMP manufacturing, collaborating with cross-functional teams, and providing technical guidance to junior staff. The role emphasizes hands-on technical expertise in mammalian cell culture and bioprocess optimization to ensure high-quality vector products for advanced cell therapy programs.

Our read on this posting3.6out of 5

benefits: 5/5
freshness: 4/5
career value: 4/5
role clarity: 5/5
pay transparency: 0/5

Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Legend Biotech US as an employer.

What you need

Advanced degree (PhD preferred, or MS) in Chemical Engineering, Bioengineering, or a related field
5-8 years (PhD) or 8+ years (MS) of experience in process development or manufacturing within a biotech or pharmaceutical setting
Hands-on experience in mammalian cell culture (HEK293, HEK293T), seed train expansion, feeding strategy, and transient transfection optimization specifically for viral vectors (Lentivirus preferred)
Demonstrated proficiency in developing and implementing bioreactor scale-up and scale-down models
Solid understanding of GMP manufacturing requirements and CMC strategies for early-phase clinical trials
Direct experience with cell and lentiviral vector technologies within the current emerging field

Nice to have

Preferred experience in handling large-scale (>50L, e.g., 200L/500L) upstream bioreactor processes
Language(s): Mandarin is a plus

What you get

Medical, dental, and vision insurance
401(k) retirement plan with a company match that vests fully on day one
Eight (8) weeks of paid parental leave after just three (3) months of employment
Paid time off policy including vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays
Flexible spending and health savings accounts
Life and AD&D insurance

Worth weighing

No salary listed, but a pay range is provided: $127,313 — $167,099 USD
The role requires a significant amount of hands-on technical expertise, which may not appeal to candidates seeking more strategic or managerial positions.
The position is focused on compliance with GMP and regulatory requirements, which may involve a rigorous work environment.

Summarised from Legend Biotech US's posting. Read the full original.

Listed by Legend Biotech US on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.

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