Cheminformatics & Synthesis Prediction
Ginkgo Bioworks Inc. · Boston, Massachusetts
Posted 22 days ago
or apply directly on Ginkgo Bioworks Inc.'s site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 22 days Ginkgo Bioworks Inc.'s roles stay open a median of 45 days
- Reposted
- No
- Salary listed
- No 75% of Ginkgo Bioworks Inc.'s roles list one
- Ghost-job risk at Ginkgo Bioworks Inc.
- high 16 stale, 0 reposted of 20 open
- Hiring momentum
- 22 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-09-17
Measured from postings appearing on and disappearing from Ginkgo Bioworks Inc.'s own greenhouse board since 2026-08-03. Full hiring picture for Ginkgo Bioworks Inc..
About this role
The Senior Engineer I, Cheminformatics & Synthesis Prediction role at Ginkgo involves developing and maintaining cheminformatics workflows that support the creation of makeable chemical spaces and reaction prediction capabilities. This hands-on position requires collaboration with chemists to translate scientific inquiries into computational workflows, focusing on reaction enumeration and predictive modeling tasks. The role emphasizes practical cheminformatics engineering rather than machine learning research, and it involves writing maintainable code and integrating cheminformatics tools into automated workflows.
- benefits
- 5/5
- freshness
- 4/5
- career value
- 4/5
- role clarity
- 5/5
- pay transparency
- 0/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Ginkgo Bioworks Inc. as an employer.
What you need
- Ph.D. in cheminformatics, computational chemistry, organic chemistry, medicinal chemistry, or a closely related quantitative field, plus 3 years of relevant industry or postdoctoral experience; or an M.S. with 6 years, or a B.S. with 9 years, of relevant experience
- Strong practical experience in cheminformatics and reaction prediction, including experience with retrosynthesis, reaction-condition prediction, synthetic accessibility, or related workflows
- Experience working with reaction SMARTS, functional-group classification, molecular representations, and chemical structure data
- Production experience with RDKit or an equivalent cheminformatics toolkit
- Experience working with large chemical or vendor building-block catalogs and understanding the trade-offs involved in coverage, scale, and data quality
- Strong Python skills and experience writing code that others can run and maintain
Nice to have
- Experience with large makeable or synthesizable chemical spaces, whether commercial or in-house
- Experience operating a combinatorial library-enumeration pipeline or reaction-prediction workflow in production
- Experience evaluating predictive models, including uncertainty estimation, calibration, applicability domain, or ranked candidate generation
- Experience with regiochemistry, stereochemistry, chemical registration systems, ELN/LIMS integration, or chemical data standards
- Experience connecting computational design to wet-lab results in a design–make–test–learn environment
What you get
- Competitive compensation
- Generous equity in a public company
- Robust benefits package including medical, dental & vision coverage
- Health spending accounts
- Voluntary benefits
- Leave of absence policies
Worth weighing
- No salary listed in the posting, but a range is provided: $115,000 - $165,000
- Return to office policy requires in-office presence 5 days a week starting October 1, 2025 for employees living within 50 miles of the office
- The role emphasizes practical cheminformatics engineering over machine learning research, which may limit exposure to cutting-edge ML techniques
Summarised from Ginkgo Bioworks Inc.'s posting. Read the full original.
Listed by Ginkgo Bioworks Inc. on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.
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