Associate Director/Director, Clinical Pharmacology and Pharmacometrics
Dianthus Therapeutics · Remote
Posted 28 days ago
or apply directly on Dianthus Therapeutics's site. We never take the application ourselves.
Is this posting real?
- This role has been open
- 28 days Dianthus Therapeutics's roles stay open a median of 45 days
- Reposted
- No
- Salary listed
- No 0% of Dianthus Therapeutics's roles list one
- Ghost-job risk at Dianthus Therapeutics
- high 3 stale, 0 reposted of 6 open
- Hiring momentum
- 10 roles opened in the last 90 days ↑ up vs. the prior 90 days
- Last confirmed on the employer's board
- 2026-09-17
Measured from postings appearing on and disappearing from Dianthus Therapeutics's own greenhouse board since 2026-08-03. Full hiring picture for Dianthus Therapeutics.
About this role
The Associate Director/Director of Clinical Pharmacology and Pharmacometrics will lead quantitative analyses to support the development of therapies for autoimmune diseases. This role involves designing and executing pharmacokinetic and pharmacodynamic models, conducting dose selection strategies, and collaborating with cross-functional teams to inform clinical development and regulatory submissions. The position requires strong modeling expertise and the ability to communicate complex data effectively to various stakeholders.
- benefits
- 1/5
- freshness
- 4/5
- career value
- 5/5
- role clarity
- 5/5
- pay transparency
- 0/5
Scored from the posting itself — how clearly the role is described, how much it says about pay and benefits, and how recently it was listed. Not a judgement of Dianthus Therapeutics as an employer.
What you need
- Ph.D. in Pharmacometrics, Pharmaceutical Sciences, Clinical Pharmacology, Bioengineering, Systems Biology, or related quantitative discipline (PharmD with relevant pharmacometrics experience also considered)
- Minimum 6–8 years of relevant industry experience in clinical pharmacology/pharmacometrics
- Demonstrated proficiency in QSP model development using MATLAB
- Strong hands-on expertise in population PK/PD modeling using NONMEM
- Proficiency in R for pharmacometric data analysis, visualization, and reporting
- Experience translating nonclinical and early clinical (SAD/MAD) data into human dose projections and Phase 2 dosing strategies
Nice to have
- Familiarity with autoimmune, inflammatory, and/or neuromuscular disease areas (e.g., SLE, Sjögren's syndrome, dermatomyositis, gMG, CIDP, MMN)
- Experience authoring pharmacometric sections of regulatory submissions (IND/CTA, briefing documents, NDA/BLA)
- Prior experience supporting subcutaneous biologic formulation/device lifecycle programs
- Experience with competitive intelligence modeling and literature-based model informed drug development (MIDD) approaches
- Prior direct interaction with FDA/EMA on clinical pharmacology or pharmacometric matters
Worth weighing
- Remote work option available
- Role involves significant cross-functional collaboration and communication with non-technical stakeholders
- Focus on quantitative modeling may limit exposure to other areas of drug development
Summarised from Dianthus Therapeutics's posting. Read the full original.
Listed by Dianthus Therapeutics on their greenhouse job board, last confirmed open on 2026-09-17. PitchMeAI is not the employer.